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- ItemSomente MetadadadosDysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials(Consel Brasil Oftalmologia, 2016) Andrade, Eric Pinheiro [UNIFESP]; Berezovsky, Adriana [UNIFESP]; Sacai, Paula Yuri [UNIFESP]; Pereira, Josenilson Martins [UNIFESP]; Rocha, Daniel Martins [UNIFESP]; Salomao, Solange Rios [UNIFESP]Purpose: To evaluate visual acuity and transient pattern reversal (PR) visual evoked potentials (VEPs) in the fellow eyes of children with strabismic and/or anisometropic amblyopia. Methods: Children diagnosed with strabismic and/or anisometropic amblyopia were recruited for electrophysiological assessment by VEPs. Monocular grating and optotype acuity were measured using sweep-VEPs and an Early Treatment Diabetic Retinopathy Study chart, respectively. During the same visit, transient PR-VEPs of each eye were recorded using stimuli subtending with a visual angle of 60', 15', and 7.5'. Parameters of amplitude (in mu V) and latency (in ms) were determined from VEP recordings. Results: A group of 40 strabismic and/or anisometropic amblyopic children (22 females: 55%, mean age = 8.7 +/- 2.2 years, median = 8 years) was examined. A control group of 19 healthy children (13 females: 68.4%, mean age = 8.2 +/- 2.6 years, median = 8 years) was also included. The fellow eyes of all amblyopes had significantly worse optotype acuity (p = 0.021) than the control group, regardless of whether they were strabismic (p = 0.040) or anisometropic (p = 0.048). Overall, grating acuity was significantly worse in the fellow eyes of amblyopes (p = 0.016) than in healthy controls. Statistically prolonged latency for visual angles of 15' and 7.5' (p = 0.018 and 0.002, respectively) was found in the strabismic group when compared with the control group. For the smaller visual stimulus (7.5'), statistically prolonged latency was found among all fellow eyes of amblyopic children (p< 0.001). Conclusions: The fellow eyes of amblyopic children showed worse optotype and grating acuity, with subtle abnormalities in the PR-VEP detected as prolonged latencies for smaller size stimuli when compared with eyes of healthy children. These findings show the deleterious effects of amblyopia in several distinct visual functions, mainly those related to spatial vision.
- ItemSomente MetadadadosPattern-reversal visual evoked potentials as a diagnostic tool for ocular malingering(Consel Brasil Oftalmologia, 2016) Soares, Tarciana de Souza [UNIFESP]; Sacai, Paula Yuri [UNIFESP]; Berezovsky, Adriana [UNIFESP]; Rocha, Daniel Martins [UNIFESP]; Watanabe, Sung Eun Song [UNIFESP]; Salomao, Solange Rios [UNIFESP]Purpose: To investigate the contributions of transient pattern-reversal visual evoked potentials in the diagnosis of ocular malingering at a Brazilian university hospital. Methods: Adult patients with suspected malingering in one or both eyes were referred for visual evoked potential testing. Data from patients' medical records were reviewed and analyzed retrospectively. Data analysis included the distance optotype visual acuity based on a ETDRS retro-illuminated chart and the transient pattern-reversal visual evoked potential parameters of latency (milliseconds) and amplitude (microvolts) for the P100 component, using checkerboards with visual subtenses of 15' and 60'. Motivations for malingering were noted. Results: The 20 subjects included 11 (55%) women. Patient ages ranged from 21 to 61 years (mean = 45.05 +/- 11.76 years