Navegando por Palavras-chave "ultraviolet radiation"
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- ItemSomente MetadadadosInfluence of cholecalciferol (vitamin D3) on the course of experimental systemic lupus erythematosus in F1 (NZBxW) mice(Wiley-Blackwell, 2000-01-01) Vaisberg, Mauro Walter [UNIFESP]; Kaneno, R.; Franco, M. F.; Mendes, N. F.; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP); Univ MariliaThe course of systemic lupus erythematosus (SLE), an autoimmune disease, is markedly affected by hormones such as estrogen and prolactin. It is well known that heavy exposure to sunlight has deleterious effects on SLE, triggering episodes of the disease. Classical explanations for this occurrence suggest that UV radiation damages DNA, which becomes immunogenic, or induces exposure of the Ro antigen in keratinocytes. in recent years, it has been shown that vitamin D3 has important effects on the immune system. Thus, we proposed an alternative hypothesis, suggesting that UV radiation, by promoting vitamin D3 synthesis, could be a factor aggravating the course of SLE after exposure to sunlight. To test this hypothesis, we injected F1(NZBxW) mice, which are prone to developing SLE, with vitamin D3, and we demonstrated a worsening of the histopathological findings in the kidney. (C) 2000 Wiley-liss, Inc.
- ItemSomente MetadadadosInfluence of photodegradation with UV radiation in biotreatment with Paecilomyces variotti on PHBV/GNS nanocomposites(Inst Engineering Technology-Iet, 2018) Montagna, Larissa Stieven [UNIFESP]; Montanheiro, Thais Larissa do Amaral [UNIFESP]; Borges, Aline Chiodi; Koga-Ito, Cristiane Yumi; Lemes, Ana Paula [UNIFESP]; Rezende, Mirabel Cerqueira [UNIFESP]Graphite nanosheets (GNSs) and poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) nanocomposites were prepared by solution casting method. This study aimed to evaluate the effects of previously phototreatment with ultraviolet (UV) radiation on the biotreatment with Paecilomyces variotti of neat PHBV and PHBV/GNS nanocomposites. Some samples of PHBV film were submitted only to biotreatment with P. variotti during 120 days