Navegando por Palavras-chave "transvaginal sonography"

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    Cervical gland area as an ultrasonographic marker for preterm delivery
    (Elsevier B.V., 2006-06-01) Pires, C. R.; Moron, A. F.; Mattar, Rosiane [UNIFESP]; Diniz, ALD; Andrade, SGA; Bussamra, LCS; Universidade Federal de São Paulo (UNIFESP)
    Objective: To assess the association between spontaneous preterm delivery (SPTD) in the general population and the measurement of the cervix length, cervical funneling, and absence of the cervical gland area (CGA). Method: A prospective cohort of 338 women carrying uncomplicated pregnancies was evaluated by transvaginal sonography between 21 and 24 weeks' gestation. Results: Measurement of cervical length with less than 20 mm and the presence of cervical funneling presented a statistically significant association with SPTD before 35 weeks. the nondetection of CGA demonstrated a strong association with SPTD before 37 weeks' (p < 0.001; OR=194.5) and before 35 weeks' gestation (p < 0.001; OR=129.6). the multiple logistic regression analysis suggested the non-detection of CGA as the only variable to reveal statistically significance association with SPTD. Conclusion: the results seem to indicate that the absence of CGA can be a new and important ultrasound marker for SPTD, to be confirmed by future multicenter investigations. (c) 2005 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
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    Ultrasonographic and morphological studies of the postmenopausal endometrium using unopposed estrogen replacement therapy with regular pause: a prospective preliminary study
    (Elsevier B.V., 2001-09-01) Patriarca, M. T.; Lima, G. R. de; Stavale, J. N.; Goncalves, Wagner Jose [UNIFESP]; Freitas, V; Soares, J. M.; Simoes, M. J.; Baracat, E. C.; Universidade Federal de São Paulo (UNIFESP)
    Hormone replacement therapy with progestogen is known to have severe side effects or complications in certain patients. Objective: the goal of this study is to evaluate the safety and efficacy of an alternative treatment regimen with a mensal pause using both transvaginal sonography (TVS) and endometrial biopsy to follow patients. Methods: A total of 30 postmenopausal women were treated with unopposed estrogen for 21 days each month followed by a regular pause of 9-10 days, and were studied prospectively for 18 months. the TVS measurements of endometrial thickness and biopsy of the endometrium were done on the 21 st day of treatment and the 7th day of the pause at 6-month intervals throughout the study. Results: There was a significant decrease of proliferative activity at all three time points during the study (6, 12 and 18 months) when tested on the 7th pause day (PD7). the percentage of patients with hyperplasia without nuclear atypia and endometrial thickness greater than or equal to8 mm was 32% at 6 months, but decreased to 22 and 19% at 12 and IS months, respectively. All cases of hyperplasia regressed after the hormonal pause throughout the treatment period. Conclusions: This study presents an alternative treatment regimen for select patients having side effects or complications from progestogen administration; however, studies evaluating the safety and efficacy of this regimen over longer time periods are necessary. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.