Navegando por Palavras-chave "symptom control"
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- ItemSomente MetadadadosPredictive factors of overall quality of life in advanced cancer patients using EORTC QLQ-C30(Expert Reviews, 2014-02-01) Cramarossa, Gemma; Zeng, Liang; Zhang, Liying; Tseng, Ling-Ming; Hou, Ming-Feng; Fairchild, Alysa; Vassiliou, Vassilios; Jesus-Garcia, Reynaldo [UNIFESP]; El-Din, Mohamed A. Alm; Kumar, Aswin; Forges, Fabien; Chie, Wei-Chu; Sahgal, Arjun; Lam, Henry; Pulenzas, Natalie; Chow, Edward; Univ Toronto; Natl Yang Ming Univ; Kaohsiung Med Univ Hosp; Cross Canc Inst; Bank Cyprus; Universidade Federal de São Paulo (UNIFESP); Tanta Univ Hosp; Reg Canc Ctr; St Etienne Univ Hosp; Natl Taiwan UnivObjective: To identify which domains/symptoms from the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) were predictive of overall quality of life (QoL) in advanced cancer patients. Methods: Four hundred and forty seven patients with brain metastases or bone metastases from seven countries were enrolled with regression analysis to determine the predictive value of the QLQ-C30 functional/symptom scores for patient reported overall QoL (question 30), overall health (question 29) and the global health status domain (questions 29 and 30). Results: Worse role functioning, social functioning, fatigue and financial problems were the most significant predictive factors for worse QoL. in the bone metastases subgroup (n = 400), role functioning, fatigue and financial problems were the most significant predictors. in patients with brain metastases (n = 47), none of the EORTC domains significantly predicted worse QOL. Conclusion: Deterioration of certain QLQ-C30 functional/symptom scores significantly contributes to worse QoL, overall health and global health status.