Navegando por Palavras-chave "supressão"

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    Cortisol salivar na avaliação do eixo hipotálamo-hipofisário-adrenal em crianças saudáveis menores de 3 anos
    (Sociedade Brasileira de Pediatria, 2007-04-01) Silva, Margarete L.; Mallozi, Marcia Carvalho [UNIFESP]; Ferrari, Giesela F.; Universidade Estadual Paulista (UNESP); Faculdade de Medicina do ABC; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: To establish reference concentration intervals for salivary cortisol in healthy children, in the morning and in the afternoon, investigating factors that interfere with the concentration measured and the possibility that circadian rhythms are present. METHODS: A controlled observational study was carried out with 91 children aged 45 days to 36 months, selected at random and living in Santo André, state of São Paulo, Brazil. Inclusion criteria were: healthy, well-nourished, free from fever and corticoid use, subdivided by age group (five subsets) at 6-month intervals. Saliva was collected during home visits in the morning and afternoon. Cortisol was radioimmunoassayed with cortisol 3-oxime-bovine albumin antiserum. RESULTS: The five subsets exhibited higher cortisol concentration during the morning than in the afternoon (p < 0.001), and this difference passed 30% from 1 year of age onwards. Mean concentrations, in nmol/L, were 557.86 (morning) and 346.36 (afternoon). A negative linear correlation was observed between morning concentrations and hours' sleep and frequency of meals (p < 0.05), and in the afternoon with anthropometric measurements (p < 0.05). CONCLUSIONS: Reference values for normal salivary cortisol in healthy children were established. At 45 days it was possible to observe circadian rhythms, which reached maturity at 12 months of life. Sleep and food deprivation increased morning cortisol levels.
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    O papel do sistema olivococlear medial em crianças portadoras de TDAH
    (Associação Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial, 2012-06-01) Pereira, Valéria Reis Do Canto; Feitosa, Maria Ângela Guimarães; Pereira, Luiz Henrique Mourão Do Canto; Azevedo, Marisa Frasson de [UNIFESP]; Universidade de Brasília Instituto de Psicologia Departamento de Processos Psicológicos Básicos; Ministério da Ciência e Tecnologia; Universidade Federal de São Paulo (UNIFESP)
    Attention deficit hyperactivity disorder (ADHD) patients show, as one of the main symptoms, an attentional impairment. Selective attention in the hearing process is the ability to understand speech in a noisy environment, which can be evaluated by several methods. One of the main approaches is the functioning of the Medial Olivocochlear Efferent System, which can be accessed by Transient-Evoked Otoacoustic Emissions (TOAE). OBJECTIVE:This study aimed at evaluating the suppression effect of contralateral noise on TOAE in ADHD (study group) and normal subjects (control group). Study Design: Case-control study. MATERIAL AND METHODS: A study with 20 children distributed in two, age- and gender-matched groups. RESULTS: No differences were found in TOAE responses between the two groups, with and without noise. CONCLUSIONS: We conclude that there were no functional differences in the Medial Olivocochlear Efferent System in the two groups analyzed.
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    Portadores de vitiligo: estudo das emissões otoacústicas e efeito de supressão
    (ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2009-02-01) Angrisani, Rosanna Mariangela Giaffredo; Azevedo, Marisa Frasson de [UNIFESP]; Pereira, Liliane Desgualdo [UNIFESP]; Lopes, Celso [UNIFESP]; Garcia, Michele Vargas [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Vitiligo is a skin disease characterized by absence of melanin due to melanocytes destruction. AIM: to study the incidence of hearing alterations in patients with vitiligo. METHOD: prospective audiological evaluation, transient-evoked otoacoustic emission recordings and study the effects of suppression in 24 patients with vitiligo. Their ages ranged from 15 to 45 years. RESULTS: 21 patients (87.5%) had normal audiometry; 2 had unilateral hearing loss in the high frequencies and 1 had cochlear moderate hearing loss in the left ear. Of these 21 subjects, 66.7% had no otoacoustic emissions, suggesting cochlear dysfunction. Only 7 patients had otoacoustic emissions present in all frequencies (29.2%) and 17 (70.8%) did not have them, and the highest rate of no otoacoustic emissions happened in the right ear of males. Regarding the suppression study, 6 subjects failed, all of them were females, and their left ears were the most affected. CONCLUSION: the findings show that patients with vitiligo, particularly males, have a greater predisposition to cochlear dysfunction, especially in the right ear. As far as the suppression effect was concerned, there was a greater alteration in the female efferent system, particularly in the left ear. Hearing alterations did not vary as far as age is concerned, type of vitiligo and time of disease progression.