Navegando por Palavras-chave "sudden cardiac death"
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- ItemAcesso aberto (Open Access)The brain-heart connection: Implications for understanding sudden unexpected death in epilepsy(Via Medica, 2009-09-01) Scorza, Fulvio Alexandre [UNIFESP]; Arida, Ricardo Mario [UNIFESP]; Cysneiros, Roberta Monterazzo [UNIFESP]; Terra, Vera C.; Sonoda, Eliza Yumi de Freitas [UNIFESP]; Albuquerque, Marly de [UNIFESP]; Cavalheiro, Esper Abrão [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Univ Presbiteriana Mackenzie; Universidade de São Paulo (USP)Epilepsy is one of the commonest neurological problems worldwide. Approximately 3% of the general population will suffer from epilepsy at some point in their lives. Unfortunately, individuals with epilepsy are at a higher risk of death than the general population, and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Information concerning risk factors for SUDEP is conflicting, but potential risk factors include young age, early onset of epilepsy, duration of epilepsy, uncontrolled seizures, seizure frequency, antiepileptic drug number and winter temperatures. Although the cause of SUDEP is still unknown, its most commonly suggested mechanisms are cardiac abnormalities during and between seizures. As the anatomical substrate of epileptic activity in the central nervous system shows a direct relation to cardiovascular alterations, this may suggest that patients with epilepsy associated with focal central nervous system lesions may face a particular risk of SUDEP. Currently, experimental and clinical data supports the importance of specific brain structures in the behavioural manifestation, the initiation and the propagation of seizures. Regarding the above findings, our research group focused on this review article that S UDEP could be related to the occurrence of specific brain structure dysfunction or anatomical change, at least in some cases. (Cardiol J 2009; 16, 5: 394-399)
- ItemAcesso aberto (Open Access)Gestão de Qualidade Empresarial: como essa teoria pode ser útil na pesquisa do fenômeno de morte súbita e inesperada na epilepsia?(Liga Brasileira de Epilepsia (LBE), 2008-03-01) Scorza, Fulvio Alexandre [UNIFESP]; Arida, Ricardo Mario [UNIFESP]; Albuquerque, Marly de [UNIFESP]; Scorza, Carla Alessandra [UNIFESP]; Cavalheiro, Esper Abrão [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de Mogi das Cruzes Núcleo de Pesquisas TecnológicasINTRODUCTION: Epilepsy is the most common neurological disorder, approximately 1% of the population worldwide have epilepsy. Moreover, people with epilepsy are more likely to die prematurely than those without epilepsy and the most common epilepsy-related category of death is sudden unexpected death in epilepsy (SUDEP). OBJECTIVES: The aim of this review is to discuss the definition, epidemiology, risk factors, etiology and preventative measures in the management of SUDEP from strategies adopted by corporate system experts. CONCLUSIONS: This is a interesting paradigm shift with significant implications for guiding research on SUDEP.
- ItemSomente MetadadadosSudden Cardiac Death in Brazil: Study Based on Physicians' Perceptions of the Public Health Care System(Wiley-Blackwell, 2012-11-01) Martinelli, Martino; De Siqueira, Sergio F.; Zimerman, Leandro I.; Neto, Vicente A.; Moraes, Antonio V.; Fenelon, Guilherme [UNIFESP]; Universidade de São Paulo (USP); Univ Fed Rio Grande do Sul; Hosp Sao Joaquim; Universidade Federal de São Paulo (UNIFESP)Background: There are no available statistical data about sudden cardiac death in Brazil. Therefore, this study has been conducted to evaluate the incidence of sudden cardiac death in our population and its implications.Methods: the research methodology was based on Thurstone's Law of Comparative Judgment, whose premise is that the more an A stimulus differs from a B stimulus, the greater will be the number of people who will perceive this difference. This technique allows an estimation of actual occurrences from subjective perceptions, when compared to official statistics. Data were collected through telephone interviews conducted with Primary and Secondary Care physicians of the Public Health Service in the Metropolitan Area of São Paulo (MASP).Results: in the period from October 19, 2009, to October 28, 2009, 196 interviews were conducted. the incidence of 21,270 cases of sudden cardiac death per year was estimated by linear regression analysis of the physicians responses and data from the Mortality Information System of the Brazilian Ministry of Health, with the following correlation and determination coefficients: r = 0.98 and r2= 0.95 (95% confidence interval 0.81.0, P < 0.05). the lack of waiting list for specialized care and socioadministrative problems were considered the main barriers to tertiary care access.Conclusions: the incidence of sudden cardiac death in the MASP is high, and it was estimated as being higher than all other causes of deaths; the extrapolation technique based on the physicians perceptions was validated; and the most important bureaucratic barriers to patient referral to tertiary care have been identified. (PACE 2012; 35:13261331)
- ItemAcesso aberto (Open Access)What are the similarities between stress, sudden cardiac death in Gallus gallus and sudden unexpected death in people with epilepsy(Academia Brasileira de Neurologia - ABNEURO, 2010-10-01) Scorza, Fulvio Alexandre [UNIFESP]; Albuquerque, Ricardo de; Arida, Ricardo Mario [UNIFESP]; Albuquerque, Marly de [UNIFESP]; Terra, Vera Cristina; Machado, Helio Rubens; Cysneiros, Roberta Monterazzo [UNIFESP]; Scorza, Carla Alessandra [UNIFESP]; Cavalheiro, Esper Abrão [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); University of São Paulo Veterinary Medicine and Animal Science School Nutrition and Animal Production Department; Universidade de São Paulo (USP); Mackenzie Presbyterian University Center of Biological Sciences and Health Program Graduate Development DisordersIndividuals with epilepsy are at higher risk of sudden unexpected death in epilepsy (SUDEP), responsible for 7.5% to 17% of all deaths in epilepsy. Many factors are current associated with SUDEP and possible effect of stress and cardiac arrhythmia are still not clear. Sudden death syndrome (SDS) in chickens is a disease characterized by an acute death of well-nourished and seeming healthy Gallus gallus after abrupt and brief flapping of their wings, similar to an epileptic seizure, with an incidence estimated as 0.5 to 5% in broiler chickens. A variety of nutritional and environmental factors have been included: but the exactly etiology of SDS is unknown. Studies had suggested that the hearts of broiler chickens are considerably more susceptible to arrhythmias and stress may induce ventricular arrhythmia and thus, sudden cardiac death. In this way, SDS in Gallus gallus could be an interesting model to study SUDEP.