Navegando por Palavras-chave "sleep apnea syndromes"
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- ItemAcesso aberto (Open Access)Computerized analysis of snoring in sleep apnea syndrome(Associação Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial, 2011-08-01) Shiomi, Fabio Koiti; Pisa, Ivan Torres [UNIFESP]; Campos, Carlos José Reis De [UNIFESP]; Instituto Federal de Educação Tecnológica de São Paulo; Universidade Federal de São Paulo (UNIFESP)The International Classification of Sleep Disorders lists 90 disorders. Manifestations, such as snoring, are important signs in the diagnosis of the Obstructive Sleep Apnea Syndrome; they are also socially undesirable. OBJECTIVE: The aim of this paper was to present and evaluate a computerized tool that automatically identifies snoring and highlights the importance of establishing the duration of each snoring event in OSA patients. MATERIAL AND METHODS: The low-sampling (200 Hz) electrical signal that indicates snoring was measured during polysomnography. The snoring sound of 31 patients was automatically classified by the software. The Kappa approach was applied to measure agreement between the automatic detection software and a trained observer. Student's T test was applied to evaluate differences in the duration of snoring episodes among simple snorers and OSA snorers. RESULTS: Of a total 43,976 snoring episodes, the software sensitivity was 99. 26%, the specificity was 97. 35%, and Kappa was 0. 96. We found a statistically significant difference (p <0. 0001) in the duration of snoring episodes (simple snoring x OSA snorers). CONCLUSIONS: This computer software makes it easier to generate quantitative reports of snoring, thereby reducing manual labor
- ItemAcesso aberto (Open Access)Obstructive sleep apnea prevents the expected difference in craniofacial growth of boys and girls(Academia Brasileira de Neurologia - ABNEURO, 2013-01-01) Juliano, Maria Ligia [UNIFESP]; Machado, Marco Antonio Cardoso [UNIFESP]; Carvalho, Luciane Bizari Coin de [UNIFESP]; Santos, Gianni Mara Silva dos; Zancanella, Edilson; Prado, Lucila Bizari Fernandes do [UNIFESP]; Prado, Gilmar Fernandes do [UNIFESP]; Universidade Federal de Sào Paulo São Paulo Hospital Department of NeurologyOBJECTIVES: It was to compare cephalometric measures of mouth-breather boys and girls and with the cephalometric pattern observed in obstructive sleep apnea syndrome (OSAS) patients. METHODS: Craniofacial measurements of lateral cephalometric radiographs obtained from 144 children aged 7-14 years were compared between boys and girls, and both were compared to cephalometric pattern of OSAS patients. RESULTS: Mouth-breather boys and girls had no gender differences regarding to craniofacial morphology while nose-breather boys and girls showed those expected differences. Nose-breather boys presented a more retruded mandible and proinclined upper incisor when compared to nose-breather girls, but mouth-breather boys and girls had no differences. The measure NS.GoGn was the only variable with an interaction with gender and breathing. CONCLUSIONS: There were no cephalometric difference in mouth breather-boys and girls related to normal growth, suggesting that oral breathing make the same craniofacial morphology and both have craniofacial morphology close to that of OSAS patients.
- ItemSomente MetadadadosSleep-Disordered Breathing Exacerbates Muscle Vasoconstriction and Sympathetic Neural Activation in Patients with Systolic Heart Failure(Lippincott Williams & Wilkins, 2016) Lobo, Denise M. L.; Trevizan, Patricia F.; Toschi-Dias, Edgar; Oliveira, Patricia A.; Piveta, Rafael B.; Almeida, Dirceu Rodrigues de [UNIFESP]; Mady, Charles; Bocchi, Edimar A.; Lorenzi-Filho, Geraldo; Middlekauff, Holly R.; Negrao, Carlos E.Background-Sleep-disordered breathing (SDB) is common in patients with heart failure (HF), and hypoxia and hypercapnia episodes activate chemoreceptors stimulating autonomic reflex responses. We tested the hypothesis that muscle vasoconstriction and muscle sympathetic nerve activity (MSNA) in response to hypoxia and hypercapnia would be more pronounced in patients with HF and SDB than in patients with HF without SDB (NoSBD). Methods and Results-Ninety consecutive patients with HF, New York Heart Association functional class II-III, and left ventricular ejection fraction <= 40% were screened for the study. Forty-one patients were enrolled: NoSDB (n=13, 46 [39-53] years) and SDB (n=28, 57 [54-61] years). SDB was characterized by apnea-hypopnea index >= 15 events per hour (polysomnography). Peripheral (10% O-2 and 90% N-2, with CO2 titrated) and central (7% CO2 and 93% O-2) chemoreceptors were stimulated for 3 minutes. Forearm and calf blood flow were evaluated by venous occlusion plethysmography, MSNA by microneurography, and blood pressure by beat-to-beat noninvasive technique. Baseline forearm blood flow, forearm vascular conductance, calf blood flow, and calf vascular conductance were similar between groups. MSNA was higher in the SDB group. During hypoxia, the vascular responses (forearm blood flow, forearm vascular conductance, calf blood flow, and calf vascular conductance) were significantly lower in the SDB group compared with the NoSDB group (P<0.01 to all comparisons). Similarly, during hypercapnia, the vascular responses (forearm blood flow, forearm vascular conductance, calf blood flow, and calf vascular conductance) were significantly lower in the SDB group compared with the NoSDB group (P<0.001 to all comparisons). MSNA were higher in response to hypoxia (P=0.024) and tended to be higher to hypercapnia (P=0.066) in the SDB group. Conclusions-Patients with HF and SDB have more severe muscle vasoconstriction during hypoxia and hypercapnia than HF patients without SDB, which seems to be associated with endothelial dysfunction and, in part, increased MSNA response.