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- ItemAcesso aberto (Open Access)Giardia lamblia e alergia respiratória: estudo em uma amostra de crianças de área urbana com frequência elevada da protozoose(Sociedade Brasileira de Pediatria, 2012-06-01) Souza, Valdênia M. O.; Sales, Iana R. F.; Peixoto, Décio Medeiros [UNIFESP]; Costa, Vláudia M. Assis; Rizzo, José A.; Silva, Almerinda R.; Camilo, Roberta Faria [UNIFESP]; Pierotti, Felipe Faria; Solé, Dirceu [UNIFESP]; Sarinho, Emanuel S. C.; Universidade Federal de Pernambuco Laboratório de Imunopatologia Keizo Asami; UFPE Laboratório de Imunopatologia Keizo Asami; UFPE Hospital das Cínicas Imunologia; UFPE Hospital das Clínicas Imunologia; UFPE Hospital das Clínicas; Universidade Federal de São Paulo (UNIFESP); UFPE; UFPE Programa de Pós-graduação em Ciências da SaúdeOBJECTIVES: There is a high incidence of intestinal parasite infection in urban areas in the Northeast of Brazil. Giardia lamblia infections have been associated with increased prevalence of cutaneous allergies and gastrointestinal disorders. However, little is known about the relationship between giardiasis and allergic diseases of the airways. The present study aimed to investigate the possible association between respiratory allergic diseases and infections by G. lamblia in children from urban areas. METHODS: This study recruited 110 patients of both sexes aged 5-15 years. Patients were administered a questionnaire evaluating clinical symptoms and were given skin tests, parasite tests and serum tests. RESULTS: A high incidence of G. lamblia was observed (45%, 50/110). Infections by this protozoan were not associated with increased risk of respiratory allergy (p = 0.075), high total IgE levels (p = 0.701), positive specific IgE tests (p = 0.250), or positive skin tests for a range of environmental allergens (p = 0.239). CONCLUSION: This study demonstrated that symptoms of asthma, skin allergy and serum markers were not associated with G. lamblia infections in this sample of children from urban areas.
- ItemSomente MetadadadosSensitisation to aeroallergens in Brazilian adolescents living at the periphery of large subtropical urban centres(Elsevier B.V., 2008-01-01) Pastorino, Antonio Carlos; Kuschnir, Fabio Chigres; Arruda, Luisa Karla de Paula [UNIFESP]; Casagrande, Rejane Rimazza Dalberto; Souza, Renata Gontijo Lima de; Dias, Gabriela Andrade Coelho; Silveira, H. H. N.; Cunha, Antonio Jose Ledo Alves da; Jacob, Cristina Miuki Abe [UNIFESP]; Solé, Dirceu [UNIFESP]; Universidade de São Paulo (USP); Universidade Federal do Rio de Janeiro (UFRJ); Secretariet Civil Def; Universidade Federal de São Paulo (UNIFESP)Objectives: To evaluate the sensitization to aeroallergens determined by skin prick test (SPT) in Brazilian adolescents, and to correlate its positivity with the diagnosis of asthma and/or rhinitis based on the written questionnaire (WQ) of ISAAC phase III study.Patients and Methods: A total of 996 adolescents (387 boys) were selected by systematic samples. A standard allergen extracts panel (positive/negative control, D pteronyssinus [Dpt], P americana [Pal, B germanica [Bg], dog, cat, fungal and grass mix) was used and its positivity compared with positive responses to asthma, rhinitis or both.Results: Positive SPT to at least one allergen was observed in 466 adolescents (46.8 %), with sensitisation to Dpt in 79.1 %. Positivity to more than one allergen occurred in 232 students (49.8 %). The frequency of positive SPTs was significantly higher among adolescents with asthma (OR = 2.16), rhinitis (OR = 1.69), and asthma and rhinitis (OR = 2.03). Positive SPT to four or more allergens were higher among asthmatics (OR = 2.6) and among adolescents with asthma and rhinitis (OR = 3).Conclusions: A high sensitisation rate to aeroallergens was observed, significantly higher among those with asthma, rhinitis or a combination of both, especially in multiple sensitisations.