Navegando por Palavras-chave "skin flap"

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    Aplicação de retalho cutâneo no tratamento cirúrgico do hemangiopericitoma canino
    (Universidade Federal de Santa Maria, 1998-03-01) Matera, Julia Maria; Sakuma, Cinthia Harumi; Tatarunas, Angélica Cecilia; Valente, Neusa Sakai; Michalany, Nílceo [UNIFESP]; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)
    Canine hemangiopericytoma is a relatively common cutaneous tumor frequently affecting the limbs. Treatment usually is local resection, limb amputation and radiation, with high rates of tumor recurrence. The medical records of 6 dogs treated at the Veterinary Teaching Hospital of the University of São Paulo between July 1994 and July 1996 were reviewed for tumor features, skin flap technique and postoperative follow up. The dogs in this study were 3 females and 3 males; the mean age was 9 years. One dog was mixed breed and the other dogs were Poodle (2); Boxer (1); German Shepherd(1) and Pekingeese(1). The majority of tumors (5 tumors) were located on the limbs and l was located on the perineal region. Skin flap techniques used were : H- plasty (2), W-plasty(1), transposition flap (2), single pedicle advancement flap (1). The sutures were removed 10 to 15 days after surgery. Five dogs had 100% viability of flap skin and necrosis ocurred in one dog which had a survival of 89% of the flap. One dog died 15 months after the surgery because of nontumor related causes. No evidence of recurrence was noted and tumor free interval ranged from 4-20 months. Wide surgical excision of the canine hemangiopericytoma seems to be an eficient therapy since no recurrence ocurred. Familiarity with techniques of skin flap creation can provide the surgeon with alternatives to close a large wound resulting from tumor excision. Skin flaps can bypass many problems in open wound management including delayed healing and greater expenses.
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    Efeitos da oxigenação hiperbárica sobre a morfologia e a quantificação do colágeno em retalhos cutâneos randômicos de ratos
    (Universidade Federal de São Paulo (UNIFESP), 2016-02-26) Rech, Fabricio Valandro [UNIFESP]; Fagundes, Djalma Jose [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objective. Evaluate the microscopic morphology, necrotic area and the collagen content in the rat skin flaps submitted to hyperbaric oxygen therapy (HBOT). Methods. Forty rats adults were divided into four groups: GE ? hair removal; GE / OHB ? hair removal undergone HBO; GER ? hair removal and will perform a skin flap (2 cm wide by 8 cm in length on the back) and GER / OHB ? hair removal, and performed skin flap and submitted to OHB. OHB (2.4 ATA) was performed for two hours, for seven consecutive days. On the eighth day the animals were anesthetized, the flaps removed and separated into three parts: the proximal, middle and distal - with respect to the pedicle fixation. The material was fixed in 10% formalin and processed for paraffin embedding, and the sections stained by HE and picrosirius-red. The blades in HE were examined under a light microscope and collagen content valued at polarizing microscope and ImageLab® software (Bio-Rad). Results. The macroscopic evaluation showed a higher area of necrosis in the three regions of the GER group regarding GE / HBO: (Proximal = 24.6 ± 10.6> 5.6 ± 1.6; Medial; 84.5 ± 5.9> 7.5 ± 3.7; Distal: 98.5 ± 3.7> 15.4 ± 2.5) compared to the GE / OHB. The microscopy study showed a major histopathological lesions in the three regions of the GER group compared to the GE / OHB (Proximal - 8.6 ± 1.2> GER / OHB = 2.4 ± 0.6; medial = 11.5 ± 2. 7> 5.4 ± 1.9 and 14.8 ± 5.3 distal => 8.1 ± 3.7. The collagen concentration was higher in the medial and distal region in GER / OHB group compared to GER (Medial: 81.5 ± 16.7> 55.5 ± 12.6; Distal: 72.2 ± 16.7> 32.8 ± 12.5). Conclusion. Hyperbaric oxygenation had favorable effects on random skin flaps in rats considering the microscopic morphology, necrotic area and collagen concentration.