Navegando por Palavras-chave "reinke edema"

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    Concentração do ácido hialurônico em pregas vocais com edema de reinke
    (Universidade Federal de São Paulo (UNIFESP), 2016-11-29) Melo, Cristiana Vanderlei de [UNIFESP]; Biase, Noemi Grigoletto de Biase [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objective: The authors investigated the concentration of hyaluronic acid in Reinke's edema in the vocal fold cover. Method: For this study a hyaluronic acid binding protein isolated from bovine nasal cartilage was used. Plates containing the binding protein were successively incubated with 32 samples Reinke?s edema and 11 female vocal folds; biotin-conjugated hyaluronic acid binding protein and europium-labeled. After release of europium from streptavidin with enhancement solution the final flourescence was measured in a fluorometer. Results: Were evaluated 19 patients with Reinke's edema, with a predominance of the female sex (94%) with mean age of 57.62 years. The concentration of hyaluronic acid in vocal folds with Reinke's edema was greater and statistically significant relative to the control. There was no statistical difference between the concentration of hyaluronic acid in the samples with Reinke's edema in relation to age, grade or smoking history.Conclusion: The study of hyaluronic acid concentration in vocal folds with Reinke's edema, we conclude that vocal folds affected by Reinke's edema have higher concentrations of hyaluronic acid in relation to normal; and the concentration of hyaluronic acid is independent of age, the degree of Reinke's edema or smoking history.