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- ItemSomente MetadadadosGrape juice concentrate alleviates epididymis and sperm damage in cadmium-intoxicated rats(Wiley, 2017) Lamas, Celina de A.; Cuquetto-Leite, Livia; da Silva, Emanueli do Nascimento; Thomazini, Bruna F.; Cordeiro, Gabriel da S.; Predes, Fabricia de S.; Golluecke, Andrea P. B. [UNIFESP]; Dolder, HeidiThe possibility of long-term grape juice concentrate (GJC) consumption conferring a protective effect against cadmium (Cd)-induced damage to the epididymis, completely preserving sperm profile, was evaluated here for the first time in the scientific literature. Male Wistar rats (n=6/per group) received an intraperitoneal Cd injection (1.2mg/Kg) at age 80days and GJC (2g/Kg) by gavage from 50days until 136days old. Groups receiving either Cd or GJC were added. An intraperitoneal injection of saline (0.9%) and water by gavage was administered in the absence of treatment with Cd or GJC. Animals were anaesthetized and exsanguinated at 136days