Navegando por Palavras-chave "papillomavirus"

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    Human papillomavirus detected in viral warts of renal transplant recipients
    (Wiley-Blackwell, 2016) Martelli-Marzagao, F. [UNIFESP]; Santos Junior, G. F.; Ogawa, M. M. [UNIFESP]; Enokihara, M. M. S. S. [UNIFESP]; Porro, A. M. [UNIFESP]; Tomimori, J. [UNIFESP]
    ObjectivesFew studies have been conducted in South America regarding the detection and genotyping of human papillomavirus (HPV) in viral warts of renal transplant recipients (RTRs). The characterization of the population most susceptible to the development of warts and the knowledge of the main HPV types in this environment prompted this study, which focuses on the detection and typing of HPV in RTRs in Brazil. MethodsFifty-eight patients with viral warts from the Hospital SAo Paulo/Federal University of SAo Paulo were included in this study. HPV was detected by polymerase chain reaction (PCR) using combinations of the following primers: PGMY 09/11, RK 91, CP 65/70, and CP 66/69. Restriction fragment length polymorphism and automated sequencing techniques were used for HPV typing. ResultsHPV was detected by PCR in 89.7% of viral wart samples. The most frequently detected HPV types included 57, 27, 1a, 2a, and 20. Other types of HPV-epidermodysplasia verruciformis were also detected, including 14, 15, 19, 20, 21, 23, 36, and 38. Rare HPV types were also detected in our environment, including RTR X1, RTR X7, and 100. The time after transplant was correlated with an increased number of lesions and beta papillomavirus genus infection. ConclusionsThe HPV types detected in the RTR population were similar to those described in immunocompetent populations. However, the diversity of the HPV types identified and the number of lesions were increased in the RTR population.
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    Human papillomavirus detected in viral warts of renal transplant recipients
    (Wiley-Blackwell, 2016) Martelli-Marzagao, F. [UNIFESP]; Santos Junior, G. F.; Ogawa, M. M. [UNIFESP]; Enokihara, M. M. S. S. [UNIFESP]; Porro, A. M. [UNIFESP]; Tomimori, J. [UNIFESP]
    ObjectivesFew studies have been conducted in South America regarding the detection and genotyping of human papillomavirus (HPV) in viral warts of renal transplant recipients (RTRs). The characterization of the population most susceptible to the development of warts and the knowledge of the main HPV types in this environment prompted this study, which focuses on the detection and typing of HPV in RTRs in Brazil. MethodsFifty-eight patients with viral warts from the Hospital SAo Paulo/Federal University of SAo Paulo were included in this study. HPV was detected by polymerase chain reaction (PCR) using combinations of the following primers: PGMY 09/11, RK 91, CP 65/70, and CP 66/69. Restriction fragment length polymorphism and automated sequencing techniques were used for HPV typing. ResultsHPV was detected by PCR in 89.7% of viral wart samples. The most frequently detected HPV types included 57, 27, 1a, 2a, and 20. Other types of HPV-epidermodysplasia verruciformis were also detected, including 14, 15, 19, 20, 21, 23, 36, and 38. Rare HPV types were also detected in our environment, including RTR X1, RTR X7, and 100. The time after transplant was correlated with an increased number of lesions and beta papillomavirus genus infection. ConclusionsThe HPV types detected in the RTR population were similar to those described in immunocompetent populations. However, the diversity of the HPV types identified and the number of lesions were increased in the RTR population.
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    Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus
    (Associação Paulista de Medicina - APM, 1997-02-01) Nicolau, Sergio Mancini [UNIFESP]; Martins, Nelson Valente [UNIFESP]; Ferraz, Paulo Eduardo [UNIFESP]; Stávale, João Norberto [UNIFESP]; Goncalves, Wagner Jose [UNIFESP]; Baracat, Edmund Chada [UNIFESP]; Lima, Geraldo Rodrigues de [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    INTRODUCTION: Male genital infection by human papillomavirus is of particular importance since it is often asymptomatic. The patient generally presents no clinical lesion. Therefore, men represent an important reservoir of virus, playing a special role in the transmission and perpetuation of the disease. PATIENTS AND METHODS: In the present prospective clinical trial study, 190 sex partners of women with genital infection by human papillomavirus, associated or not with cervical intraepithelial neoplasia, were investigated. All patients were unaware of or denied the presence of a genital lesion. RESULTS: Cytologic examination revealed koilocytosis in 9 cases (4.7%) in the urethra and in 3 cases (1.6%) in the corona of the glans and the distal prepuce. Peniscopy with the previous use of 5% acetic acid revealed white lesions in 97.9% of the patients. Toluidine blue stained most of the lesions. At least one fragment revealed koilocytosis in the histopathologic study of 97 cases (51.05%). CONCLUSION: The three methods complement one another, allowing a more precise diagnosis of this infection in men.