Navegando por Palavras-chave "p53 gene"

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    Association between the p53 arginine/arginine homozygous genotype at codon 72 and human papillomavirus E6/E7 mRNA expression
    (Elsevier Brazil, 2017) Silva Chuery, Ana Carolina [UNIFESP]; Cotrim Guerreiro da Silva, Ismael Dale [UNIFESP]; Lascasas Ribalta, Julisa Chamorro [UNIFESP]; de Gois Speck, Neila Maria [UNIFESP]
    Objective: To evaluate the association between p53 polymorphisms and human papillomavirus (HPV) E6/E7 mRNA expression. Methods: We analyzed 175 cervical samples from women aged 16-69 years old who were tested for HPV E6/E7 mRNA expression (NucliSENS (R) EasyQ (R) HPV). The samples were divided into three groups: positive (n = 75) those with positive HPV E6/E7 mRNA expression and positive high-risk HPV Hybrid Capture (HR-HC) test