Navegando por Palavras-chave "open fetal surgery"

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    The Almodin-Moron trocar for uterine entry during fetal surgery
    (Karger, 2006-01-01) Almodin, C. G.; Moron, A. F.; Cavaliero, S.; Yamashita, A.; Hisaba, W.; Piassi, J.; Universidade Federal de São Paulo (UNIFESP); Materbaby Reprod Humana & Genet
    Objective: Compare the use of a newly designed and reusable metal trocar for initial uterine entry with the disposable Tulipan-Bruner trocar in creation of a hysterotomyforfetal surgery. Methods:Six consecutive patients undergoing hysterotomy for intrauterine repair of myelomeningocele were randomized to uterine entry either with the Tulipan-Bruner trocar or with the Almodin-Moron trocar. Blood loss was estimated by the primary surgeon. Results: There was no statistically significant difference in the uterine entry times between the trocars. Blood loss was estimated to be approximately the same. the Almodin-Moron trocar was judged to provide easy handling with good safety. Conclusions: the AlmodinMoron trocar provides a uterine entry during creation of a hysterotomythat is as quick and causes as little trauma as the Tulipan-Bruner trocar. Copyright (c) 2006 S. Karger AG, Basel.
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    Histological evidence of reparative activity in chorioamniotic membrane following open fetal surgery for myelomeningocele
    (Spandidos Publ Ltd, 2017) Carvalho, Natalia S. [UNIFESP]; Moron, Antonio F. [UNIFESP]; Menon, Ramkumar; Cavalheiro, Sergio [UNIFESP]; Barbosa, Mauricio M. [UNIFESP]; Milani, Herbene J. [UNIFESP]; Ishigai, Marcia M. [UNIFESP]
    An increased understanding of the reparative process in fetal membrane following surgical techniques may be helpful to decrease the risks to mother and fetus and avoid adverse pregnancy outcomes. The present study discusses histological evaluation of the fetal membrane following open fetal surgery. Chorioamniotic membranes (n=10) were obtained following birth from pregnancies that underwent open fetal surgery for myelomeningocele. The collagen distribution was quantified using picrosirius-polarization method comparing the suture site with non-suture site. The differences between the collagen fiber percentages at the two sites was evaluated by the paired t-test with P<0.05. The mean gestational age of fetal surgery was 26.09 +/- 0.3 and 33.81 +/- 0.82 weeks at birth. The picrosirius red sign was more intense at the suture site, primarily associated with collagen type 1. Collagen observed in the surgical area was significantly increased (13.22 +/- 2.84%) compared with the non-surgical area (6.16 +/- 1.09%
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    Procedure-related complications of open vs endoscopic fetal surgery for treatment of spina bifida in an era of intrauterine myelomeningocele repair: systematic review and meta-analysis
    (Wiley, 2016) Araujo Junior, E. [UNIFESP]; Eggink, A. J.; Van den Dobbelsteen, J.; Martins, W. P.; Oepkes, D.
    Objective To assess and compare the rate of procedure-related complications after intrauterine treatment of spina bifida by endoscopic surgery and by open fetal surgery. Methods Systematic literature searches in PubMed and SCOPUS databases were performed on 20 September 2015 to identify randomized controlled trials and observational studies on treatment of human spina bifida by endoscopic or open fetal surgery techniques. Only studies with >= 10 cases that were published in or after 2000 were included in the meta-analysis in order to reduce the risk of bias. Primary outcomes (complete dehiscence, focal dehiscence and/or markedly thin hysterotomy scar