Navegando por Palavras-chave "nefrolitíase"
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- ItemAcesso aberto (Open Access)Efeito de doses elevadas de vitamina D3 associada à suplementação de cálcio em modelo experimental de nefrolitíase(Sociedade Brasileira de Nefrologia, 2014-06-01) Ramos, Maria Fátima de Paula; Santana, Luciane Gomes de; Razvickas, Clara Versolato; Teixeira, Vicente de Paulo Castro [UNIFESP]; Schor, Nestor [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Introduction:There is little information in the literature relating supplementary oral usage of vitamin D and calcium to the development of kidney stones. Objective:To evaluate the effect of high dose, 200 IU of vitamin D3 (V) with calcium supplementation (Ca). Methods:Experimental model consists of insertion of pellets into the bladder of rats. V was administered for 30 days with or without Ca. The rats were divided in 6 groups: 1. Sham, 2. Pellets control; 3. V control; 4. Pellets + V; 5. Pellets + Ca and 6. Pellets + Ca + V. Results:50% and 17% decreases bladder stones formation in groups 5 and 6, p < 0.005 comparing with the group 2 were observed. There was no hypercalcemia or hypercalciuria in all groups. We observed a significant decrease in calciuria in group 6 (p = 0.03). Conclusion:The administration of the V associated with Ca significantly decreased the formation of stones and caused a significant reduction in urinary calcium, suggesting a protection in the lithogenic pathophysiology.
- ItemAcesso aberto (Open Access)Litíase urinária e gestação(Sociedade Brasileira de Nefrologia, 2014-09-01) Korkes, Fernando; Rauen, Eduardo Costa; Heilberg, Ita Pfeferman [UNIFESP]; Faculdade de Medicina do ABC; Hospital Israelita Albert Einstein; Hospital São Luiz; Universidade Federal de São Paulo (UNIFESP)The diagnosis of urolithiasis during pregnancy is common, even though no additional measures are required in asymptomatic cases. Renal colic or complications of urinary lithiasis occur more frequently during the last months of pregnancy, and there are several particularities for the diagnosis and treatment of this subset of women. The present manuscript aim to review the current knowledge concerning this subject and present authors personal experience.
- ItemAcesso aberto (Open Access)Pain determinants of pain in autosomal dominant polycystic kidney disease(Sociedade Brasileira de Nefrologia, 2013-09-01) Nishiura, José Luiz [UNIFESP]; Eloi, Samara Rodrigues Moreira [UNIFESP]; Heilberg, Ita Pfeferman [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Pain is the most common symptom reported by ADPKD patients, afflicting approximately 60% of cases and may result from renal hemorrhage, calculi, urinary tract infections, cyst rupture, or due to stretching of the capsule or traction of the renal pedicle. We have recently investigated pain patterns in AD-PKD patients using a translated version of a pain questionnaire specific for AD-PKD population. The questionnaire revealed that 67% patients with ADPKD exhibited some type of pain. The findings of that study emphasized that pain appeared early in the course of ADPKD, when patients still exhibited preserved renal function. In the present study, a multivariate logistic regression analysis disclosed that renal volume (9-fold increased risk) and nephrolithiasis (4-fold increased risk) were the most important determinant factors for pain in ADPKD patients with preserved renal function, after adjustments for the presence of hypertension and duration of the disease.