Navegando por Palavras-chave "myelitis"
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- ItemAcesso aberto (Open Access)Clinical and epidemiological profiles of non-traumatic myelopathies(Assoc Arquivos Neuro- Psiquiatria, 2016) Vieira de Rezende Pinto, Wladimir Bocca [UNIFESP]; Sgobbi de Souza, Paulo Victor [UNIFESP]; Cristino de Albuquerque, Marcus Vinicius [UNIFESP]; Dutra, Livia Almeida [UNIFESP]; Pedroso, Jose Luiz [UNIFESP]; Povoas Barsottini, Orlando Graziani [UNIFESP]Non-traumatic myelopathies represent a heterogeneous group of neurological conditions. Few studies report clinical and epidemiological profiles regarding the experience of referral services. Objective: To describe clinical characteristics of a non-traumatic myelopathy cohort. Method: Epidemiological, clinical, and radiological variables from 166 charts of patients assisted between 2001 and 2012 were compiled. Results: The most prevalent diagnosis was subacute combined degeneration (11.4%), followed by cervical spondylotic myelopathy (9.6%), demyelinating disease (9%), tropical spastic paraparesis (8.4%) and hereditary spastic paraparesis (8.4%). Up to 20% of the patients presented non-traumatic myelopathy of undetermined etiology, despite the broad clinical, neuroimaging and laboratorial investigations. Conclusion: Regardless an extensive evaluation, many patients with non-traumatic myelopathy of uncertain etiology. Compressive causes and nutritional deficiencies are important etiologies of non-traumatic myelopathies in our population.
- ItemAcesso aberto (Open Access)Neuropsychiatric Lupus in clinical practice(Assoc Arquivos Neuro- Psiquiatria, 2016) Alessi, Helena [UNIFESP]; Dutra, Livia Almeida [UNIFESP]; Braga-Neto, Pedro; Pedroso, Jose Luiz [UNIFESP]; Toso, Fabio Fieni [UNIFESP]; Kayser, Cristiane [UNIFESP]; Barsottini, Orlando Graziani Povoas [UNIFESP]Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multiple organs, characterized by the production of autoantibodies and the development of tissue injury. The etiology of SLE is partially known, involving multiple genetic and environmental factors. As many as 50% of patients with SLE have neurological involvement during the course of their disease. Neurological manifestations are associated with impaired quality of life, and high morbidity and mortality rates. Nineteen neuropsychiatric syndromes have been identified associated with SLE, and can be divided into central and peripheral manifestations. This article reviews major neuropsychiatric manifestations in patients with SLE and discusses their clinical features, radiological findings and treatment options.