Navegando por Palavras-chave "inhalation"

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    Anxiolytic-like effects of rose oil inhalation on the elevated plus-maze test in rats
    (Elsevier B.V., 2004-02-01) Almeida, R. N. de; Motta, S. C.; Faturi, C. D.; Catallani, B.; Leite, JR; Univ Fed Paraiba; Universidade Federal de São Paulo (UNIFESP)
    The effect of rose oil inhalation (1.0%, 2.5%, and 5.0% w/w) on the elevated plus-maze (EPM) test was investigated in adult male rats and compared with the effect of diazepam (DZP) (1.0 and 2.0 mg/kg) administered intraperitoneally 30 min before testing. Exposure to rose oil produced an anxiolytic-like effect similar to DZP (anxiolytic reference drug). Thus, at some concentrations, rose oil significantly increased the number of visits to and time spent in the open arms of the EPM. Anxiolytic-like properties of rose oil were observed using the EPM, being consistent with other behavioral and clinical studies. (C) 2003 Elsevier Inc. All rights reserved.
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    Behavioral effects of essential oil of Citrus aurantium L. inhalation in rats
    (Sociedade Brasileira de Farmacognosia, 2008-12-01) Leite, Mariana P. [UNIFESP]; Fassin Junior, Jaime [UNIFESP]; Baziloni, Eliane Maria de Freitas [UNIFESP]; Almeida, Reinaldo Nobrega de; Mattei, Rita [UNIFESP]; Leite, Jose Roberto [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Federal da Paraíba Laboratório de Tecnologia Farmacêutica
    The orange essential oil (OEO) and its components obtained from Citrus aurantium L. (Rutaceae) has been attracting interest due to its sedative and relaxing actions. In the present study, rats previously exposed to OEO at the concentrations of 1.0%; 2.5% and 5.0%, w/w, by inhalation during 7 minutes in acrylic boxes were evaluated in two anxiety models: elevated plus maze (EPM) and open-field. The OEO at the concentration of 2.5% increased both the time of the animals in the open arms of the EPM and the time of active social interaction in the open-field being longer than that of the diazepam group (1.5 mg/kg i.p). In conclusion, the decrease in the level of emotionality of the animals observed in the two experimental models suggests a possible central action, which is in agreement with the phytochemical profile of the oil under study, since it showed the presence of limonene (96.24%) and mircene (2.24%), components with a well-known depressant activity on the central nervous system.