Navegando por Palavras-chave "immunohistochemical"

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    Immunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses
    (Pagepress Publ, 2011-01-01) Moraes, Luis Otavio Carvalho de [UNIFESP]; Lodi, Fabio Redivo [UNIFESP]; Gomes, Thiago Simao [UNIFESP]; Marques, Sergio Ricardo [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Lancellotti, Carmen Lucia Penteado; Rodriguez-Vazquez, Jose Francisco; Merida-Velasco, Jose Ramon; Alonso, Luis Garcia [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Santa Casa São Paulo; Univ Complutense Madrid
    The objective was to study the morphology of the articular disc and analyse the immunohistochemical expression of types I and III collagen markers in the temporomandibular joint (TMJ) disc of human foetuses of different gestational ages. Twenty TMJ from human foetuses supplied by Universidade Federal de Uberaba with gestational ages from 17 to 24 weeks were studied. the gestational age of the foetuses was determined by measuring the crown-rump (CR) length. Macroscopically, the foetuses were fixed in 10% formalin solution and dissected by removing the skin and subcutaneous tissue and exposing the deep structures. Immunohistochemical markers of type I and III were used to characterize the existence of collagen fibres. Analysis of the immunohistochemical markers of types I and III collagen revealed the presence of heterotypical fibril networks.
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    P27 expression in epithelial ovarian tumors
    (Elsevier B.V., 2004-05-01) Patah, LEM; Camarotto, K. C.; Goncalves, Wagner Jose [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Womens Hlth Reference Ctr
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    Pruritic papular eruption and eosinophilic folliculitis associated with human immunodeficiency virus (HIV) infection: A histopathological and immunohistochemical comparative study
    (Elsevier B.V., 2012-08-01) Junqueira Magalhaes Afonso, Joao Paulo [UNIFESP]; Tomimori, Jane [UNIFESP]; Michalany, Nilceo Schwery [UNIFESP]; Nonogaki, Suely; Porro, Adriana Maria [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Adolfo Lutz Inst
    Background: Among the papular-pruriginous dermatoses related to human immunodeficiency (HIV) infection, two entities remain poorly differentiated leading to confusion in their diagnosis: HIV-related pruritic papular eruption (HIV-PPE or prurigo) and eosinophilic folliculitis (HIV-EF).Objective: To establish histopathological and immunohistochemical parameters to differentiate between two conditions associated with HIV infection, the pruritic papular eruption (HIV-PPE) and eosinophilic folliculitis (HIV-EF).Methods: Clinically typical HIV-PPE (18 cases) and HIV-EF (10 cases) cases were compared with each other in terms of the following topics: clinical and laboratory features (gender, age, CD4+ cell and eosinophil count), histopathological features (hematoxylin-eosin and toluidine blue staining) and immunohistochemical features (anti-CD1a, anti-CD4, anti-CD7, anti-CD8, anti-CD15, anti-CD20, anti-CD30, antiCD68/macrophage and anti-S-100 reactions).Results: Among the HIV-EF patients, we found an intense perivascular and diffuse inflammatory infiltration compared with those patients with HIV-PPE. the tissue mast cell count by toluidine staining was higher in the HIV-EF patients, who also presented higher expression levels of CD15 (for eosinophils), CD4 (T helper), and CD7 (pan-T lymphocytes) than the HIV-PPE patients.Limitations: Only quantitative differences and not qualitative differences were found.Conclusions: These data indicate that HIV-related PPE and EF could possibly be differentiated by histopathological and immunohistochemical findings in addition to clinical characteristics. in fact, these two inflammatory manifestations could be within the spectrum of the same disease because only quantitative, and not qualitative, differences were found. (J Am Acad Dermatol 2012;67:269-75.)