Navegando por Palavras-chave "hyaline cartilage"
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- ItemAcesso aberto (Open Access)Aspectos moleculares dos esteroides sexuais sobre a cartilagem e os ossos(Associação Médica Brasileira, 2012-08-01) Wolff, Roberta Bastos [UNIFESP]; Gomes, Regina Célia Teixeira [UNIFESP]; Verna, Carina [UNIFESP]; Maioral, Gabriela Carolina Carozi Cristofani [UNIFESP]; Rampazo, Thaís Cristina [UNIFESP]; Simões, Ricardo Santos [UNIFESP]; Baracat, Edmund Chada [UNIFESP]; Soares Júnior, José Maria [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)In Brazil, the increase in the reported cases of degenerative diseases of articular cartilage is 20% per year, meaning that 200,000 Brazilians develop degenerative joint diseases every year, which have a negative impact on bone mass. This study shows evidence that hormone production of sexual steroids (estrogens, progestogens, and androgens) have an influence on cartilage quality, as well as on bone mass. Therefore, this review aimed to analyze literature data on the molecular and genic action of sexual steroids on hyaline cartilage and bone physiology, as well as osteoarthritis interference on the quality of these structures.