Navegando por Palavras-chave "gastrointestinal"

Agora exibindo 1 - 2 de 2
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Avaliação da lidocaína tópica como pré-medicação para a endoscopia digestiva alta em crianças
    (Sociedade de Pediatria de São Paulo, 2009-12-01) Machado, Rodrigo Strehl [UNIFESP]; Viriato, Airton; Miranda, Áurea Cristina Portorreal [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); HICF Divisão de Apoio Diagnóstico e Terapêutico
    OBJECTIVE: This study aims to evaluate the efficacy of topical lidocaine as an adjuvant drug to sedatives in children and adolescents undergoing digestive endoscopies. METHODS: 80 patients (49 females and 31 males, 12±3 years old) were randomly allocated into placebo (n=40) or lidocaine group (n=40). One patient was excluded from each group after allocation. Two puffs of either 10% lidocaine or placebo (tannic acid 0.5%) were sprayed into the oropharynx before the infusion of propofol. Patients were monitored during the procedure and answered a questionnaire after the procedure to evaluate sore throat and the medicine used as pre-medication. The primary outcome measure was propofol dose. Time spent in the procedure room, in the procedure and the incidence of complications were secondary outcome measures. RESULTS: Demographic data (age, sex and endoscopy indication) were evenly distributed in each group. The dose of propofol was not different between patients and controls (placebo group 3.1±1.1 and lidocaine group 2.9±1.3mg/kg; p=0.69), even considering the total dose (p=0.33). The time spent in the procedure room was longer for the placebo group than for the lidocaine group (23±7 versus 20±5 minutes; 95%CI of the difference: 0.47-5.89 minutes, p=0.02). There was no difference between groups regarding procedure duration, complications incidence and tolerability. CONCLUSIONS: Topic anesthetic medication reduces the time spent in the procedure room without increasing the incidence of side effects (NCT00521703).
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Avaliação do teste rápido da urease conservado em geladeira
    (Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia - IBEPEGE Colégio Brasileiro de Cirurgia Digestiva - CBCD Sociedade Brasileira de Motilidade Digestiva - SBMD Federação Brasileira de Gastroenterologia - FBGSociedade Brasileira de Hepatologia - SBHSociedade Brasileira de Endoscopia Digestiva - SOBED, 2000-07-01) Ornellas, Laura Cotta [UNIFESP]; Cury, Marcelo de Souza [UNIFESP]; Lima, Vinícius Machado de [UNIFESP]; Ferrari, Angelo Paulo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    The rapid urease test is an accurate and cheap method, which results are readily available, and broadly used for routine Helicobacter pylori infection diagnosis. Aim - The evaluation of rapid urease test stored in refrigerator at 4 °C (SRUT) compared to regular rapid urease test. Patients and Method - Endoscopic biopsies were obtained from gastric antrum in 104 consecutive patients. Diagnosis of Helicobacter pylori infection was accomplished by rapid urease test, histology and rapid urease test stored (kept in refrigerator by a period ranging from 1 to 8 days). Results - Infection was considered present if both rapid urease test and histology were positive. Helicobacter pylori was present in 45/104 patients (42%). Rapid urease test stored had specificity comparable to rapid urease test (93%), with sensitivity of 88%. Conclusion - We concluded that rapid urease test can be stored in refrigerator for up to 1 week, without loss of clinical applicability, and that can make the test even easier to use for routine Helicobacter pylori tests in a busy endoscopy unit.