Navegando por Palavras-chave "ftir"

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    Espectroscopia no FTIR: uma aplicabilidade na área de saúde
    (Universidade Federal de São Paulo (UNIFESP), 2016-09-30) Neves, Karina Ferreira [UNIFESP]; Alves, Maria Teresa de Seixas Alves [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objective: The main goal of this study is through the technique of spectroscopy vibrational molecular in the medium infrared, check the technique potential at the healthcare area. Results: We could observe that this analyses technique can map complex biological samples trough the interaction of eletromagnetic radiation with the substance, determining the energy levels of atoms and molecules, and lastly finding the biochemical composition of the sample. Based in biochemical?s information contained in the FTIR?s images, it is possible generate images of spacial distribution of several components of one specific sample ( like DNA proteins, collagen, among others) with high level of spacial resolution. A great advantage are that are not necessary large and complexes preparations of the samples. Conclusions: The Fourier Transform in Medium Infrared (FTIR) allows the global analysis of the samples with an resolution at the celular level and recently studies have showed that the image generated by the FTIR allows to view the biological?s distribution of multiples molecules of interest to analysis of tissues without pre-analytical modifications of the sample by coloration, as well as, information of the molecular?s structure. So, multiples markers can be identified from the generation of these images trough the FTIR, besides the, exact discrimination of healthy tissues and tumoral tissues; which accordingly leads us to consider the technique as a molecular histopathological tool