Navegando por Palavras-chave "excessive sleepiness"
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- ItemAcesso aberto (Open Access)Estudo da capacidade de manter o alerta em pacientes com fibromialgia por meio do teste da manutenção da vigília(Sociedade Brasileira de Reumatologia, 2008-02-01) Ribeiro Sobrinho, Djalma Gomes [UNIFESP]; Roizenblatt, Suely [UNIFESP]; Lopes, Antonio Carlos [UNIFESP]; Teixeira, Roberto Cordeiro A. [UNIFESP]; Tufik, Sergio [UNIFESP]; Universidade Estadual de Ciências da Saúde de Alagoas Faculdade de Medicina; Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: To assess in an objective way the degree of alertness in patients with fibromyalgia through the Maintenance Wakefulness Test ( MWT). METHOD: Fifteen patients with fibromyalgia and 15 age and sex- matched healthy controls were sequentially selected. The inclusion criteria for fibromyalgia were the presence of at least 11 of the 18 tender points and diffuse pain during three months prior to evaluation. All participants answered the Epworth Sleepiness Scale (ESS) and underwent four 20 minutes sessions of MWT scheduled at 2-hour intervals. Mean sleep latency higher than 20 minutes or lower than 10 minutes was considered normal or pathological, respectively. RESULTS: Although ESS scores did not differ between fibromyalgia patients and controls, the fibromyalgia group showed a significant decrease in the sleep latency by MWT ( 9.9 ± 4.6 and 14.9 ± 5.1, respectively, p = 0.01). Pathological results were obtained in 66.7% of the patients, in comparison to 26.7% of the controls ( p = 0.03). CONCLUSION: In this pilot study, patients with fibromyalgia showed decrease in the sleep latency by the Wakefulness Maintenance Test.
- ItemSomente MetadadadosRecognizable clinical subtypes of obstructive sleep apnea across international sleep centers: a cluster analysis(Oxford Univ Press Inc, 2018) Keenan, Brendan T.; Kim, Jinyoung; Singh, Bhajan; Bittencourt, Lia [UNIFESP]; Chen, Ning-Hung; Cistulli, Peter A.; Magalang, Ulysses J.; McArdle, Nigel; Mindel, Jesse W.; Benediktsdottir, Bryndis; Arnardottir, Erna Sif; Prochnow, Lisa Kristin; Penzel, Thomas; Sanner, Bernd; Schwab, Richard J.; Shin, Chol; Sutherland, Kate; Tufik, Sergio [UNIFESP]; Maislin, Greg; Gislason, Thorarinn; Pack, Allan I.Study Objectives: A recent study of patients with moderate-severe obstructive sleep apnea (OSA) in Iceland identified three clinical clusters based on symptoms and comorbidities. We sought to verify this finding in a new cohort in Iceland and examine the generalizability of OSA clusters in an international ethnically diverse cohort. Methods: Using data on 972 patients with moderate-severe OSA (apnea-hypopnea index [AHI] >= 15 events per hour) recruited from the Sleep Apnea Global Interdisciplinary Consortium (SAGIC), we performed a latent class analysis of 18 self-reported symptom variables, hypertension, cardiovascular disease, and diabetes. Results: The original OSA clusters of disturbed sleep, minimally symptomatic, and excessively sleepy replicated among 215 SAGIC patients from Iceland. These clusters also generalized to 757 patients from five other countries. The three clusters had similar average AHI values in both Iceland and the international samples, suggesting clusters are not driven by OSA severity