Navegando por Palavras-chave "distonia cervical"

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    Head tremor in patients with cervical dystonia: different outcome?
    (Academia Brasileira de Neurologia - ABNEURO, 2008-12-01) Godeiro-Junior, Clecio [UNIFESP]; Felício, André Carvalho [UNIFESP]; Aguiar, Patricia C. [UNIFESP]; Borges, Vanderci [UNIFESP]; Silva, Sonia M.a. [UNIFESP]; Ferraz, Henrique B. [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: The association of cervical dystonia (CD) with other movement disorders have been already described, but data on clinical outcome regarding these patients are scant. The aim of this paper was to investigate whether patients with CD and head tremor (HT) would have a different outcome regarding to botulinum toxin type-A (BTX-A) treatment response and clinical and demographic parameters. METHOD: We retrospectively evaluated 118 medical charts of patients with CD and divided them into two groups: with (HT+) and without (HT-) head tremor. We compared the following clinical and demographic parameters: age at onset, disease duration, progression of symptoms, etiology, familial history, presence of hand tremor. We also analyzed the response to BTX-A according to Tsui score in both groups. RESULTS: The occurrence of head tremor in our sample was of 38.2%. The occurrence of postural hand tremor in the patients from the HT+ group was higher than in the HT- one (p=0.015) and if we compare BTX-A response in each group, we observe that patients with HT present a better outcome in a setting of longer follow-up. In HT+ group, Tsui score pre treatment was 10 (6-12.5) and after follow-up was 8 (5.5-10.5); p<0.001. In HT- group there was no significant difference 9 (7-12) in pre treatment and after follow-up; p=0.07. CONCLUSION: According to our data it seems that head tremor may influence the clinical outcome or treatment response with BTX-A in patients with CD.
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    Retrocollis, anterocollis or head tremor may predict the spreading of dystonic movements in primary cervical dystonia
    (Academia Brasileira de Neurologia - ABNEURO, 2009-06-01) Godeiro-Junior, Clecio [UNIFESP]; Felício, André Carvalho [UNIFESP]; Aguiar, Patrícia Maria de Carvalho [UNIFESP]; Borges, Vanderci [UNIFESP]; Silva, Sonia Maria Azevedo [UNIFESP]; Ferraz, Henrique Ballalai [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    BACKGROUND AND PURPOSE: Few studies have attempted to develop clinical predictors for cervical dystonia (CD) aiming at progression of the dystonic movement. METHOD: We retrospectively evaluated 73 patients with primary CD who underwent treatment with Botulinum toxin type-A (BTX-A). The patients were assembled in two groups according to the spread of dystonia during follow-up: spreading and non-spreading CD. We performed a binary logistic regression model using spreading of cervical dystonia as dependent variable aiming to find covariates which increase the risk of spreading. RESULTS: Our logistic regression model found the following covariates and their respective risk ratios: time of disease >18.5 months=2.4, retrocollis=1.9, anterocollis=1.8, head tremor=1.6. CONCLUSION: Time of disease >18.5 months, retrocollis, anterocollis and head tremor may predict spreading of dystonic movement to other regions of the body in CD patients.