Navegando por Palavras-chave "discoid lupus erythematosus"
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- ItemSomente MetadadadosEarly discoid lupus erythematosus protects against renal disease in patients with systemic lupus erythematosus: longitudinal data from a large Latin American cohort(Sage Publications Ltd, 2017) Pons-Estel, G. J.; Aspey, L. D.; Bao, G.; Pons-Estel, B. A.; Wojdyla, D.; Saurit, V.; Alvarellos, A.; Caeiro, F.; Haye Salinas, M. J.; Sato, Emilia Inoue [UNIFESP]; Soriano, E. R.; Costallat, L. T. L.; Neira, O.; Iglesias-Gamarra, A.; Reyes-Llerena, G.; Cardiel, M. H.; Acevedo-Vasquez, E. M.; Chacon-Diaz, R.; Drenkard, C.Objectives The objective of this study was to examine whether early discoid lupus erythematosus (DLE) would be a protective factor for further lupus nephritis in patients with systemic lupus erythematosus (SLE). Methods We studied SLE patients from GLADEL, an inception longitudinal cohort from nine Latin American countries. The main predictor was DLE onset, which was defined as physician-documented DLE at SLE diagnosis. The outcome was time from the diagnosis of SLE to new lupus nephritis. Univariate and multivariate survival analyses were conducted to examine the association of DLE onset with time to lupus nephritis. Results Among 845 GLADEL patients, 204 (24.1%) developed lupus nephritis after SLE diagnosis. Of them, 10 (4.9%) had DLE onset, compared to 83 (12.9%) in the group of 641 patients that remained free of lupus nephritis (hazard ratio 0.39
- ItemSomente MetadadadosEyelid discoid lupus erythematosus and contact dermatitis: a case report(Blackwell Publishing Ltd, 2004-09-01) Trindade, Maria Angela Bianconcini [UNIFESP]; Alchorne, Alice de Oliveira de Avelar [UNIFESP]; Costa, Enilde Borges [UNIFESP]; Enokihara, Mílvia Maria Simões e Silva [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)We report a patient with discoid lupus erythematosus (DLE) and associated allergic contact dermatitis (ACD) in the eyelids. In women, ACD caused by nail varnish is frequent and often seen in the eyelids. ACD caused by drugs (e.g. neomycin) is also frequent in this region. However, DLE with periorbital presentation without evidence of systemic or other cutaneous involvement is rare.