Navegando por Palavras-chave "cats"

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    Evaluation of the Perkins (R) handheld applanation tonometer in the measurement of intraocular pressure in dogs and cats
    (Wiley-Blackwell, 2009-09-01) Andrade, Silvia Franco; Cremonezi, Tatiana; Miranda Zachi, Cristiane Aparecida; Lonchiati, Caroline Ferreira; Amatuzzi, Juliana Dalarrosa; Sakamoto, Keila Priscilla; Arruda Mello, Paulo Augusto de [UNIFESP]; Univ Oeste Paulista; Universidade Federal de São Paulo (UNIFESP)
    ObjectiveTo evaluate and to validate the accuracy of the Perkins
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    In vitro susceptibility of antifungal drugs against Sporothrix brasiliensis recovered from cats with sporotrichosis in Brazil
    (Oxford Univ Press, 2016) Nogueira Brilhante, Raimunda Samia [UNIFESP]; Rodrigues, Anderson Messias [UNIFESP]; Costa Sidrim, Jose Julio [UNIFESP]; Gadelha Rocha, Marcos Fabio [UNIFESP]; Pereira, Sandro Antonio; Ferreira Gremiao, Isabella Dib; Pacheco Schubach, Tania Maria; de Camargo, Zoilo Pires [UNIFESP]
    Sporotrichosis is an important subcutaneous mycosis of humans and animals. Classically, the disease is acquired upon traumatic inoculation of Sporothrix propagules from contaminated soil and plant debris. In addition, the direct horizontal transmission of Sporothrix among animals and the resulting zoonotic infection in humans highlight an alternative and efficient rout of transmission through biting and scratching. Sporothrix brasiliensis is themost virulent species of the Sporothrix schenckii complex and is responsible for the long-lasting outbreak of feline sporotrichosis in Brazil. However, antifungal susceptibility data of animal-borne isolates is scarce. Therefore, this study evaluated the in vitro activity of amphotericin B, caspofungin, itraconazole, voriconazole, fluconazole, and ketoconazole against animal-borne isolates of S. brasiliensis. The susceptibility tests were performed through broth microdilution (M38-A2). The results show the relevant activity of itraconazole, amphotericin B, and ketoconazole against S. brasiliensis, with the following MIC ranges: 0.125-2, 0.125-4 and 0.0312-2 mu g/ml, respectively. Caspofungin was moderately effective, displaying higher variation in MIC values (0.25-64 mu g/ml). Voriconazole (2-64 mu g/ml) and fluconazole (62.5-500 mu g/ml) showed low activity against S. brasiliensis strains. This study contributed to the characterization of the in vitro antifungal susceptibility of strains of S. brasiliensis recovered from cats with sporotrichosis, which have recently been considered the main source of human infections.