Navegando por Palavras-chave "beta-Carotene"
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- ItemSomente MetadadadosDietary predictors of serum total carotene in low-income women living in São Paulo, south-east Brazil(Cambridge Univ Press, 2009-11-01) Tomita, Luciana Y.; Almeida, Lana C.; Roteli-Martins, Cecilia; D'Almeida, Vania [UNIFESP]; Cardoso, Marly A.; BRINCA Study Team; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP); Hosp Leonor Mendes BarrosObjective Dietary intake and nutritional status of antioxidant vitamins have been reported to protect against some cancers the objective of the present study was to assess the correlations between serum levels of carotenoids (including beta-, alpha- and gamma-carotene), lycopene, retinol, alpha- and gamma-tocopherols, and dietary intakes estimated by an FFQ, among low-income women in the Brazilian Investigation into Nutrition and Cervical Cancer Prevention (BRINCA) study.Design Cross-sectional study of data for 918 women aged 21-65 years participating in the BRINCA study in São Paulo city. Multiple linear regression models were used with serum nutrient levels as the dependent variable and dietary intake levels as the independent variable, adjusted for confounding factors.Results in energy-adjusted analyses, the intakes of dark green and deep yellow vegetables and fruits (partial R(2) = 4.8%), total fruits and juices (partial R(2) = 1.8%), vegetables and fruits (partial R(2) = 1.8%), carrots (partial R(2) = 1.4%) and citrus fruits and juices only (partial R(2) = 0.8%) were positively correlated only with serum total carotene levels, after adjusting for serum total cholesterol concentration, age, hospital attended, smoking status. BMI and presence of cervical lesions Multiple-adjusted serum levels of carotenoids were positively correlated with intake quartiles of dark green and deep yellow vegetables and fruits and total fruits and juices independent of smoking status.Conclusions the intake of specific fruits and vegetables was an independent predictor of serum total carotene levels in low-income women living in São Paulo
- ItemSomente MetadadadosLipodystrophy, lipid profile changes, and low serum retinol and carotenoid levels in children and adolescents with acquired immunodeficiency syndrome(Elsevier B.V., 2010-06-01) Beraldo Battistini, Tania Regina; Sarni, Roseli Oselka Saccardo [UNIFESP]; Suano de Souza, Fabiola Isabel [UNIFESP]; Pitta, Tassiana Sacchi; Fernandes, Ana Paula; Hix, Sonia; Affonso Fonseca, Fernando Luiz; Tardini, Priscila Chemiotti; Santos, Valter Pinho dos; Lopez, Fabio Ancona [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objective: To assess serum retinol and levels of carotenoids in children and adolescents with acquired immunodeficiency syndrome (AIDS) and to correlate low serum retinol and carotenoid levels with the presence of lipodystrophy, lipid profile changes, lipid peroxidation, and insulin resistance.Methods: A cross-sectional, controlled observational study was carried out with 30 children and adolescents with AIDS (mean age 9.1 y) receiving antiretroviral therapy (median length of treatment 28.4 mo), including 30 uninfected healthy controls matched forage and gender. Clinical and laboratory assessments were performed to determine nutritional status, presence of lipodystrophy, serum concentrations of retinol, beta-carotene, lycopene, lipid profile (high-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triacylglycerols), lipid peroxidation (thiobarbituric acid-reactive substances), glycemia, and serum insulin (homeostasis model assessment for insulin resistance, cutoff point >3). Statistical analysis was done with chi-square test and Student's t test.Results: Lipodystrophy was observed in 53.3% of patients with AIDS, and dyslipidemia was detected in 60% and 23% of subjects with human immunodeficiency virus and control subjects, respectively (P = 0.004). A higher prevalence of retinol deficiency (60% versus 26.7%, P = 0.009) and beta-carotene deficiency (23.3% versus 3.3%, P = 0.026) was found in the group with human immunodeficiency virus than in the control group. No correlation was found for low retinol and beta-carotene levels, changes in lipid and glucose metabolism, or lipodystrophy in children and adolescents with AIDS.Conclusion: Despite the high frequency of dyslipidemia, lipodystrophy, and retinol and beta-carotene deficiencies, it was not possible to demonstrate a correlation of these findings with lipid peroxidation and insulin resistance. More studies are needed to investigate the causes of retinol and beta-carotene deficiencies in this population and the clinical consequences of these findings. (C) 2010 Elsevier Inc. All rights reserved.