Navegando por Palavras-chave "anxiolytics"

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    The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis
    (Associação Brasileira de Divulgação Científica, 2001-02-01) Andreatini, R.; Blanchard, C.; Blanchard, R.; Brandão, M.l.; Carobrez, A.p.; Griebel, G.; Guimarães, F.s.; Handley, S.l.; Jenck, F.; Leite, Jose Roberto [UNIFESP]; Rodgers, J.; Schenberg, L.c.; Da Cunha, C.; Graeff, F.g.; Universidade Federal do Paraná Departamento de Farmacologia Laboratório de Fisiologia e Farmacologia do Sistema Nervoso Central; University of Hawaii Department of Neurobiology; University of Hawaii Department of Psychology; Universidade de São Paulo (USP); Universidade Federal de Santa Catarina Departamento de Farmacologia; Central Nervous System Research Department Sanofi Synthelabo; Aston University Institute of Pharmaceutical Sciences; Hoffmann-La Roche Ltd.; Universidade Federal de São Paulo (UNIFESP); University of Leeds Department of Psychology Ethopharmacology Laboratory; Universidade Federal do Espírito Santo Centro de Biomedicina Departamento de Ciências Fisiológicas
    This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of fear/anxiety. A challenge for future research is to establish a good correlation between animal models and nosological classification.
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    Factors associated with antidepressant, anxiolytic, and other psychotropic medication use to treat psychiatric symptoms in the city of São Paulo, Brazil
    (Lippincott Williams & Wilkins, 2014-05-01) Blay, Sergio L. [UNIFESP]; Fillenbaum, Gerda G.; Pitta, Jose C. [UNIFESP]; Peluso, Erica T.; Universidade Federal de São Paulo (UNIFESP); Univ Bandeirante São Paulo; Duke Univ
    The objective of this study was to examine the prevalence and characteristics of adult psychotropic medication use in São Paulo, Brazil. Information on lifetime and 12-month psychotropic medication use, and psychiatric status was obtained from a representative sample of 2000 adults aged 18-65 years in São Paulo, Brazil. Lifetime and 12-month use of psychotropic medications was 16.8 and 7.1%, respectively. of the 22.8% of patients with current psychiatric problems, 29.5% reported lifetime use and 15.8% (5.6% of the sample) reported 12-month use (anxiolytics: 2.7%, antidepressants: 1.8%, alternative medicines: 0.9%, antipsychotics: 0.4%, mood stabilizers: 0.4%, hypnotics: 0.3%; multiple class use occurred). the most frequent prescribers were psychiatrists and general practitioners. Determinants of use included identification as a psychiatric case (four-fold increased odds), being female (three-fold increase), age (4-5% per additional year), and lower odds if married. Education, employment status, and birth in São Paulo were not associated with use. Income did not affect anxiolytic use, but antidepressant and alternative medicine use was associated with higher income. These results show that psychotropic drug use was comparatively low. Only 15.8% of patients with psychiatric problems reported recent psychotropic use. Comparable with other studies, use was greater among women and increased with age.