Navegando por Palavras-chave "Varizes Esofágicas E Gástricas"

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    Detecção De Varizes Gástricas E De Trombose De Veia Porta Em Doentes Portadores De Esquistossomose Hepatoesplênica Após Tratamento Endoscópico Com Erradicação De Varizes Esofágicas
    (Universidade Federal de São Paulo (UNIFESP), 2017-05-25) Aniche, Marcelo Finavaro [UNIFESP]; Colleoni Neto, Ramiro [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    an expressive problem of public health. The main impact of this disease on health occurs in patients with hepatosplenic form, high morbidity and mortality. Currently in the literature, there is a lack of data on long-term follow-up of these patients, especially those submitted to exclusive endoscopic treatment with eradication of esophageal varices. Objective: To evaluate the incidence of variceal vein thrombosis and gastric varices as well as the association between these events. Methods: We evaluated 50 patients diagnosed with schistosomiasis in the hepatosplenic form who underwent to endoscopic treatment with eradication of esophageal varices. Patients followed in our clinic from April 1, 1983 to December 31, 2016. Inclusion criterion was a minimum follow-up period of 24 months after eradication of esophageal varices, endoscopic and ultrasonographic abdominal Doppler examinations; Patients with liver disease and/or cirrhosis of another etiology were excluded. Results: We identified gender equality with mean age of 52 years and outpatient follow-up averaged 181 months. Regarding gastric varices, eight patients had primary gastric varices and 18 developed secondary ones after the eradication. The mean time of onset of gastric varices after eradication was 103 months. When analyzing ultrasonography, we observed that three patients had portal vein thrombosis and during follow-up was detected in 23 patients, the mean time of thrombus onset after esophageal variceal eradication was 69 months. We observed that portal vein thrombosis generated was 5.25 times more likely to present gastric varices compared to those without thrombosis (CI [1.4, 21.9], Fisher's Exact Test = 0.01). The mortality rate was 10%, with three deaths due to to high varicose digestive hemorrhage. Conclusion: We consider that the follow-up of the patients should be long-lasting, since the formation of portal vein thrombosis was approximately five years on average, and the average onset of gastric variceswas eight years; In addition, we conclude that the appearance of gastric varices is intimately related to portal thrombosis, and these events should be evaluated in the follow-up and treatment of the disease, given its high frequencies and may be associated with morbidity an mortality.