Navegando por Palavras-chave "Translucência nucal"

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    O papel da translucência nucal no rastreamento de cardiopatias congênitas
    (Sociedade Brasileira de Cardiologia - SBC, 2006-09-01) Bruns, Rafael Frederico [UNIFESP]; Moron, Antonio Fernandes [UNIFESP]; Murta, Carlos Geraldo Viana [UNIFESP]; Gonçalves, Luís Flávio De Andrade [UNIFESP]; Zamith, Marina Maccagnano [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Clínica Materno-Fetal; Vitória Medifetus
    OBJECTIVE: Assess the accuracy of the nuchal translucency (NT) measurement between 11 and 13 weeks and 6 days of gestation as a sonographic marker to screen for congenital heart defects (CHD). METHODS: Multicentric retrospective study, analyzing single pregnancies from euploid fetuses. NT measurement was performed in the first trimester, when fetuses had from 45 to 84 mm of crown-rump length (CRL), according to the criteria established by the Fetal Medicine Foundation. Cases were followed until 1 month after delivery to verify the presence of CHD. RESULTS: 3,664 pregnancies were analyzed and 20 newborns had CHD diagnosed until the first month of life (prevalence of 0.55%). The median NT of the fetuses with CHD was 1.70 mm and 1.60 mm for fetuses without CHD, however no significant difference was found (Mann-Whitney test, p > 0.05). The sensitivity of NT in detection of CHD varied from 15% to 20%, with a range of false positive probability from 86.4% to 97.9%, depending on the cut-off point used. However, the odds ratio was high, compared to the classic indications of echocardiography, ranging from 4.7 to 33.7 according to the cutt-off point. CONCLUSION: In spite of the low sensitivity of the test, enlarged NT is an important risk factor for CHD and should be used in prenatal screening for CHD.
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    Trissomia do cromossomo 9 associada com aumento da translucência nucal: correlação ultra-sonográfica e anatomopatológica ¾ relato de um caso
    (Colégio Brasileiro de Radiologia e Diagnóstico por Imagem, 2001-04-01) Murta, Carlos Geraldo Viana [UNIFESP]; Merçon-de-vargas, Paulo Roberto; Universidade Federal de São Paulo (UNIFESP); Universidade Federal do Espírito Santo; Universidade Federal do Espírito Santo Centro Biomédico Departamento de Patologia
    We report a case of prenatal diagnosis of trisomy 9 in a fetus presenting increased translucency thickness (9.1 mm) observed on an ultrasound scan performed at 12 weeks pregnancy and confirmed by cariotype analysis of biopsy material obtained from the chorionic villi. Multiple trisomy 9 characteristic abnormalities were detected by ultrasound and confirmed by autopsy and histopathological examination. Although rare, trisomy 9 should be included in the list of chromosomic anomalies associated with increased translucency.