Navegando por Palavras-chave "Titanium"
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- ItemSomente MetadadadosDeposição De Filmes De Dlc Dopados Com Nanopartículas De Prata Por Processo Assistido A Plasma Para Aplicações Biomédicas(Universidade Federal de São Paulo (UNIFESP), 2018-07-31) Oliveira, Adriano De [UNIFESP]; Massi, Marcos [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)This Work Was Developed Aiming To Contribute For Improvement Of Alloy Ti6al4v Biointegration, Through The Deposition Of Doped Dlc Films With Silver Nanoparticles, Using A Silicon Interlayer. The Doping Was Conducted With The Use Of Plasma Enhanced Chemical Vapor Deposition " Pecvd Process, With A Silver Hollow Cathode Conjugated. Experiments Were Carried Out With The Argon Flow Ranging From 20 To 80 Sccm, For Evaluation Of Its Influence On Film Adhesion. The Adherence Of These Films Was Studied When Deposited Right On Carbonitrided Ti6al4v Alloy Too. The Main Characterization Methods Used Were Raman Spectroscopy, Atomic Force Microscopy " Afm, Scanning Electron Microscopy " Sem, Secondary Ion Mass Spectroscopy " Sims, Scratch Test, Hardness Test Vdi " 3198 And Nanohardness. Lastly, In Vivo Tests Were Conducted With Wistar-Epm Rats, For Evaluation Of The Alloy Ti6al4v Substrate Biointegration In 3 Conditions: Polished, Covered With Dlc Film And Covered With Silver-Doped Dlc Film. The Results Showed The Doping
- ItemAcesso aberto (Open Access)Estudo de biocompatibilidade do titânio recoberto com nanofilmes de carbono e prata(Universidade Federal de São Paulo (UNIFESP), 2018-07-26) Placias, Flavio Gomes [UNIFESP]; Koh, Ivan Hong Jun [UNIFESP]; Matieli, José Elias; http://lattes.cnpq.br/0350866868370257; http://lattes.cnpq.br/6695612966568322; Universidade Federal de São Paulo (UNIFESP)Introduction: The main barriers to new prosthetic materials are rejection and infection associated with the implant. Among the materials, titanium (Ti) substrate has been widely used due to its biocompatibility and mechanical properties. However, its biocompatibility and biointegration have been questioned in the literature. Objectives: The present study aimed to improve the biocompatibility and biointegration of Ti by coating its surface with carbon nanofilm Diamondlike Carbon (DLC) and to promote microbicide capacity with silver (Ag) nanoparticles. Methods: Coatings were performed with Plasma Technology. PlasmaEnhanced Chemical Vapor Deposition (PECVD) was the method used to apply the nanofilms coatings on Ti plates. The physical characterization of the plate surface was performed by Atomic Force Microscopy (AFM) and the microbicide capacity was analyzed by culture. The biocompatibility and biointegration were studied in rats (WistarEPM, n = 24) that received the implant of the plates in the abdominal wall. Animals were reoperated after 7, 28, 90 and 180 days. Tissue integration by AMF, histology and macroscopy were monitorized.Results: The AMF presented plates surfaces modifications after nanocoating. None of the coating groups demonstrated microbicide activity. The macroscopy showed tissue adhesion and no signs of rejection. This adhesion was confirmed by the AMF. The histology showed signs of chronic inflammation that did not prevent biointegration. Conclusions: The results showed that the nanocoating enabled the implanthost interaction, but did not alter the Ti biocompatibility. In addition, the Ag deposition, under the determinated conditions, did not demonstrated the expected antimicrobial effect.
- ItemSomente MetadadadosGenotoxicity of corrosion eluates obtained from endosseous implants(Lippincott Williams & Wilkins, 2007-03-01) Ribeiro, Daniel Araki [UNIFESP]; Matsumoto, Mariza Akemi; Marques Padovan, Luis Eduardo; Marques, Mariangela Esther Alencar; Salvadori, Daisy Maria Favero; Universidade Federal de São Paulo (UNIFESP); Univ Sagrado Coracao; Univ Estadual PaulistaPurpose: Commercially pure titanium alloys are currently used as metallic biomaterials in implantology. Corrosion phenomena appear to play a decisive role in metallic implant long-term behavior. Thus, the goal of this study was to examine the genotoxic potential of corrosion eluates obtained from dental implants using Chinese ovary hamster cells in vitro by the single-cell gel (comet) assay. This technique detects deoxyribonucleic acid strand breaks in individual cells in alkaline conditions.Materials and Methods: the materials tested included 3 dental implants commercially available. Each of the tested materials was corroded in a solution consisting of equal amounts of acetic acid and sodium chloride (0.1 M) for 1, 3, 7, 14, and 21 days. the Chinese ovary hamster cultures were then exposed to all corrosion eluates obtained from endosseous dental implants for 30 minutes at 37 degrees C.Results: None of the eluates was found to exhibit genotoxicity, regardless of the type of dental implant used.Conclusion: the results suggest that all dental implants tested in this study did not induce deoxyribonucleic acid breakage as depicted by the single-cell gel (comet) assay.
- ItemAcesso aberto (Open Access)May titanium spiral tacks contribute to intra-abdominal adhesion formation?(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2012-06-01) Goldenberg, Alberto [UNIFESP]; Rivas, Carlos Eduardo; Schvartsman, Gustavo; Universidade Federal de São Paulo (UNIFESP)PURPOSE: To verify if titanium spiral tacks may contribute to intra-abdominal adhesion formation in rabbits. METHODS: Ten New Zealand white rabbits were used. Through videolaparoscopic surgery two titanium spiral tacks (ProTack®, Covidien®) were applied in the right flank. After 30 days the animals were submitted to evaluate peritoneal cavity by videolaparoscopy. RESULTS: No adhesion was found where the titanium spiral tacks were placed. CONCLUSION: Titanium spiral tacks for fixation do not cause adhesions in rabbits.
- ItemAcesso aberto (Open Access)Osteossínteses com hastes intramedulares em crianças(Sociedade Brasileira de Ortopedia e Traumatologia, 2009-10-01) Fernandes, Helio Jorge Alvachian [UNIFESP]; Saad, Eduardo Abdalla [UNIFESP]; Reis, Fernando Baldy dos [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)The authors present a comprehensive review of the literature emphasizing the use of flexible intramedullary nails in the treatment of fractures in children, focusing the treatment of femoral shaft and forearm fractures and emphasizing the importance of the non-surgical approach. Children's age and weight threshold are not well defined for the use of the method. The removal of implants is a controversial matter in the literature, with a trend towards keeping the implants.
- ItemSomente MetadadadosThe role of fluoride on the process of titanium corrosion in oral cavity(Springer, 2012-10-01) Noguti, Juliana [UNIFESP]; De Oliveira, Flavia [UNIFESP]; Peres, Rogerio Correa; Renno, Ana Claudia Muniz [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Univ Monte Serrat; Santos Catholic UnivTitanium is known to possess excellent biocompatibility as a result of corrosion resistance, lack of allergenicity when compared with many other metals. Fluoride is well known as a specific and effective caries prophylactic agent and its systemic application has been recommended widely over recent decades. Nevertheless, high fluoride concentrations impair the corrosion resistance of titanium. the purpose of this article is to summarize the current data regarding the influence of fluoride on titanium corrosion process in the last 5 years. These data demonstrate noxious effects induced by high fluoride concentration as well as low pH in the oral cavity. Therefore, such conditions should be considered when prophylactic actions are administrated in patients containing titanium implants or other dental devices.