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    Assessment of the hypnotic/sedative effects and toxicity of Passiflora edulis aqueous extract in rodents and humans
    (Wiley-Blackwell, 1991-12-01) Maluf, E.; Barros, HMT; Frochtengarten, Mario Luiz [UNIFESP]; Benti, R.; LEITE, JR; Universidade Federal de São Paulo (UNIFESP)
    Passiflora species are used in folk medicine as hypnotic and sedative treatments. in this study the hypnotic-sedative effects and toxicity of Passiflora edulis were assessed in rats and mice and in healthy volunteers. It was verified that some samples of Passiflora edulis had a nonspecific central nervous system depressant effect. Furthermore, hepatobiliary and pancreatic toxicity to animals and humans were detected.