Navegando por Palavras-chave "Sleep disturbances"
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- ItemAcesso aberto (Open Access)Influência de alterações do sono, transtornos mentais comuns, Síndrome de Burnout e qualidade de vida no desempenho acadêmico de estudantes de medicina: um estudo multicêntrico(Universidade Federal de São Paulo (UNIFESP), 2016-08-19) Medeiros, José Givaldo Melquiades de [UNIFESP]; Citero, Vanessa de Albuquerque [UNIFESP]; http://lattes.cnpq.br/9798707175891242; http://lattes.cnpq.br/1409052578771992; Universidade Federal de São Paulo (UNIFESP)Introduction: sleep alterations, quality of life impairment and other psychological distress in medical students have been described in the literature with higher rates compared to the population at large. Objective: the present study aimed to assess the direct and mediated effect of quality of life, common mental disorders and burnout syndrome, and sleep alterations (excessive daytime sleepiness and sleep quality) on self-perceived academic performance of Medical students. Method: a sample of students of four Medical schools in the North East region of Brazil was used. Students from the first, fourth, eighth and twelfth semesters answered the scales and one demographic questionnaire. The statistics were calculated by SPSS and AMOS, using structural equations modelling to test the relations between the variables. Results: the paper 1 shows a literature review on sleep alterations, common mental disorders, including anxiety and depression and burnout syndrome in Medical students. On paper 2, the relation between quality of life of medical students with burnout syndrome and common mental health disorders and demographic data was studied. It was confirmed the relation between these variables and with female students, older students and the ones in more advanced periods of the course, with poorer quality of life, more burnout and common mental health disorders. On paper 3, the results pointed out to a moderate effect on sleep alterations on academic performance, with complete mediation of quality of life. The paper 4 points out that poor sleep quality has impacted positively on TMC; and this has impacted positively in emotional exhaustion (Burnout) and negatively on selfperceived academic performance. Low quality of sleep and excessive daytime sleepiness have impacted negatively in self-perceived academic performance. Conclusion: it was highlighted that quality of life, burnout and common mental disorders interfere in the relation between sleep alterations (sleep quality and excessive daytime sleepiness) and self-perceived academic performance.
- ItemSomente MetadadadosSleep and sleepiness among Brazilian shift-working bus drivers(Marcel Dekker Inc, 2004-01-01) Santos, Eduardo Henrique Rosa [UNIFESP]; Mello, Marco Tulio de [UNIFESP]; Pradella-Hallinan, Márcia Lurdes de Cássia [UNIFESP]; Luchesi, Ligia [UNIFESP]; Pires, Maria Laura Nogueira [UNIFESP]; Tufik, Sergio [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)The aim of this study was to evaluate daytime and nighttime sleep, as well as daytime and nighttime sleepiness of professional shift-working bus drivers. Thirty-two licensed bus drivers were assessed by nocturnal and diurnal polysomnography (PSG) recording and multiple sleep latency testing (MSLT) sessions. Sleep length was shorter and sleep efficiency reduced during daytime sleep compared with nighttime sleep. Thirty-eight percent of the drivers had indices of obstructive apnea and hypopnea syndrome (>5/h sleep) during nighttime and daytime sleep; more drivers snored during daytime than nighttime sleep (50% vs. 35%, p < 0.05), and 38% of the drivers evidenced periodic leg movements. the MSLT revealed that 42 and 38% of the bus drivers met the criteria for sleepiness when the test was conducted during the day and night, respectively. the daytime as compared to nighttime sleep of shift-working bus drivers was shorter and more fragmented and was associated in many with evidence of excessive sleepiness. Respiratory disorder was a common finding among the professional shift-working bus drivers. All these sleep deficiencies may adversely affect on the job driving performance.
- ItemSomente MetadadadosSleep disturbance induced by substance P in mice(Elsevier B.V., 2006-02-28) Andersen, Monica Levy [UNIFESP]; Nascimento, Danielle da Cunha [UNIFESP]; Machado, Ricardo Borges [UNIFESP]; Roizenblatt, Suely [UNIFESP]; Moldofsky, Harvey; Tufik, Sergio [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Ctr Sleep & ChronobiolSubstance P (SP) and neurokinins have been implicated in modulating pain and mood but little is known about their effect on sleep-wake behavior. the purpose of the present study was to examine the possible involvement of SP in sleep-wake mechanisms without activation of painful responses. Electrophysiological recordings of the sleep-wake cycle were conducted in C57BL/6J male mice that had intracerebral ventricular cannula inserted for drug administration. Initially, in order to determine the highest dose of SP that would not induce nociceptive response, 10 animals per group received administration of either SP doses or artificial cerebrospinal fluid (CSF-sham group) through the carmula and were assessed by the hot plate test. the sleep-wake cycle of two other groups of mice was recorded for 24 It before (baseline) and after receiving CSF (n= 10) or SP-1 mM (n = 11), dose that had been determined in the previous hot plate test. SP interfered with sleep, when compared to baseline and to sham group, by reducing sleep efficiency, increasing latency of sleep and the number of awakening bouts. To examine the reversal of SP effects, eight mice were administered with an NK1 receptor antagonist before SP administration. Prior administration of the NK1 antagonist prevented the disturbances in sleep. Conclusions: the results suggest that SP produces disturbances in sleep, likely mediated by the NK1 receptor. (c) 2005 Elsevier B.V. All rights reserved.