Navegando por Palavras-chave "Right ventricular hypertrophy"

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    Bandagem ajustável do tronco pulmonar: comparação de dois métodos de hipertrofia aguda do ventrículo subpulmonar
    (Sociedade Brasileira de Cirurgia Cardiovascular, 2006-12-01) Assad, Renato Samy; Rodriguez, Miguel Quintana; Abduch, Maria Cristina; Valente, Acrísio Sales; Andrade, José L. [UNIFESP]; Krieger, Jose Eduardo; Barbero-marcial, Miguel; Universidade de São Paulo (USP); Hospital Universitário de Fortaleza; Universidade Federal de São Paulo (UNIFESP); Hospital Sírio Libanês Laboratório de Ecocardiografia
    OBJECTIVE: This study compares ventricular hypertrophy induced by continuous versus intermittent systolic overload of the pulmonary ventricle (RV) of young goats. METHODS: Three groups of seven goats were used (control, continuous, and intermittent). Systolic overload was maintained for 96 hours in the continuous group, while the intermittent group suffered four 12-hour periods of systolic overload, alternating with 12-hour resting periods. Echocardiographic and hemodynamic evaluations were performed every day. The animals were then killed for myocardial water content and weight evaluation. RESULTS: Both study groups achieved significant increases in RV mass (p<0.05). However, significant increases of the septum mass were observed only in the Intermittent Group (p<0.05). A greater increase in the RV wall thickness was observed in the Intermittent Group (p<0.05). There was a significant difference in RV diastolic volume between the two groups (p= 0.01), with a greater RV dilation in the Continuous Group after 24 hours of continuous overload (p< 0.03). In both groups, the RV ejection fraction was maintained within the normal range throughout the protocol. A smaller RV perimeter was observed in the Intermittent Group after 96 hours of systolic overload (p<0.05). There was no significant difference in RV myocardial water content between the study groups and the Control Group. CONCLUSIONS: Adjustable pulmonary artery bandages permit rapid RV hypertrophy in both groups. Nevertheless, it is more efficient in the Intermittent Group. This study suggests that preparation of the pulmonary ventricle with intermittent systolic overload might provide better results for the 2-stage arterial switch operation.