Navegando por Palavras-chave "Rheological behavior"

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    Clay minerals: Properties and applications to dermocosmetic products and perspectives of natural raw materials for therapeutic purposes-A review
    (Elsevier Science Bv, 2017) Dias Moraes, Jemima Daniela [UNIFESP]; Alina Bertolino, Silvana Raquel; Cuffini, Silvia Lucia [UNIFESP]; Ducart, Diego Fernando; Bretzke, Pedro Eriberto; Leonardi, Gislaine Ricci [UNIFESP]
    Clay minerals are layered materials with a number of peculiar properties, which find many relevant applications in various industries. Since they are easily found everywhere, they are particularly attractive due to their economic viability. In the cosmetic industry, clay minerals are often used as excipients to stabilize emulsions or suspensions and to modify the rheological behavior of these systems. They also play an important role as adsorbents or absorbents, not only in cosmetics but also in other industries, such as pharmaceuticals. This reviewer believes that since this manuscript is presented as covering topical applications that include pharmaceuticals, some types of clay minerals should be considered as a potential material to be used as drug delivery systems. We review several applications of clay minerals to dermocosmetic products, relating them to the underlying properties of these materials and exemplifying with a number of clay minerals available in the market. We also discuss the use of clay minerals in topically-applied products for therapeutic purposes, specially for skin treatment and protection.
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    Green Coffea arabica L. seed oil influences the stability and protective effects of topical formulations
    (Elsevier B.V., 2015-01-01) Wagemaker, Tais A. L.; Silva, Silas A. M. [UNIFESP]; Leonardi, Gislaine R. [UNIFESP]; Maia Campos, Patricia M. B. G.; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)
    Green Coffea arabica L. seed oil (GCO) has been used as an active ingredient in many skin care products, due to its properties as an emollient, improver of skin hydration and absorbent of UVB radiation. However, to obtain a stable, effective and pleasant formulation containing variable amounts of GCO it is necessary to know specific chemical characteristics of the combined ingredients. Thus, this study evaluated rheological behavior, presence of liquid crystals (LCs) and skin protective effects of GCO-containing formulations aiming to correlate these parameters with GCO concentrations by using a principal component analysis (PCA). Formulations containing GCO or not (0-15%) were submitted to physical stability assays by determinations of rheological behavior after 90 days storage, detection of LCs by polarized light microscopy and in vitro determination of the sun protection factor (SPF). in vivo protective effects in mice were evaluated with biophysical techniques and histological analysis. Data were correlated using PCA. Despite the low SPF values, GCO addition to formulations resulted in significant and proportional increases of these values. It is concluded that formulation stability and skin protective properties are influenced by GCO but desirable effects are only possible when GCO is present in high concentrations. (C) 2014 Elsevier B.V. All rights reserved.