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- ItemAcesso aberto (Open Access)Avaliação de resultados clínicos e de ressonância magnética do uso do hialuronato de sódio associado a manitol em pacientes portadores de condropatia patelar dolorosa(Universidade Federal de São Paulo (UNIFESP), 2018-07-06) Angelini, Felipe Bertelli [UNIFESP]; Astur, Diego da Costa [UNIFESP]; Paulo Santoro Belangero; http://lattes.cnpq.br/0399504221133550; http://lattes.cnpq.br/6230616550486112; http://lattes.cnpq.br/5341104603126750; Universidade Federal de São Paulo (UNIFESP)Purpose: to evaluate the outcome of the treatment of chondral lesion grade II and III of patellar cartilage with intra-articular use of hyaluronic acid after six months. The primary end point is assessing pain (VAS), quality of life (SF-36), and knee function (Lysholm and Kujala score). The secondary outcome is to evaluate chondral injury through a comparative magnetic resonance (MRI) study. Methods: Prospective case series study of 31 knees with physiological alignment showing grade II and III patellar chondral injury. Patellofemoral physical examination; radiographic imaging, computed tomography, and magnetic resonance imaging; and knee functional and quality of life scores (Lysholm, Kujala, and EVA) were used prior to the application of 6 ml of hyaluronic acid and after three and six months of treatment. Results: On average, patients evaluated presented 30.8 years. VAS for pain decreased from 5.3 to 2.7 points after six months of treatment (p <0.05). Kujala and Lysholm functional knee score also showed significant improvement during evaluated periods. (p<0.05) There was improvement in pain and emotional well-being scales when evaluating the SF-36 score (p <0.05). There was no significant change during MRI injury classification before and after treatment. Conclusion: Patients with anterior knee pain with grade II or III patellar chondral injury presented significant pain improvement, patellofemoral physical examination (Clarke and Rabot maneuvers), functional knee scores (Lysholm and Kujala), and pain and emotional well-being scales from SF-36 score after six months. (p <0.05) There was no statistical difference between MRI ICRS chodral injury classification before and after six months’ follow-up. (p> 0.05)