Navegando por Palavras-chave "Parkinson?s disease"
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- ItemAcesso aberto (Open Access)Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment(Academia Brasileira de Neurologia - ABNEURO, 2014-06-01) Chagas, Marcos Hortes N.; Moriyama, Tais Silveira [UNIFESP]; Felício, André Carvalho [UNIFESP]; Sosa, Ana Luisa; Bressan, Rodrigo Affonseca [UNIFESP]; Ferri, Cleusa Pinheiro [UNIFESP]; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP); Hospital Israelita Albert Einstein Instituto Israelita de Ensino e Pesquisa; National Institute of Neurology and Neurosurgery of MéxicoObjective : To test the hypothesis that severity of cognitive impairment modifies the association between depression and Parkinson’s disease (PD). Method : One-phase population-based door-to-door surveys. This is a secondary analysis of 1,451 people aged 65 years and older with cognitive impairment living in defined catchment areas. Depression was estimated according to ICD-10, self-reported PD, disability according to WHODAS-II and cognitive status according to the CSI-D. Results : The mean age of the sample was 79.3 years old and most (69%) were women. Of the total sample, 16.1% had depression and it was significantly higher among participants with PD. There was an increase on the ORs of the association between depression and PD with decreased scores in the cognitive test (Adjusted OR from 0.98 to 8.04). Conclusion : The association between depression and PD increases with the severity of the cognitive impairment.
- ItemAcesso aberto (Open Access)Fluency in Parkinson's disease: disease duration, cognitive status and age(Academia Brasileira de Neurologia - ABNEURO, 2014-05-01) Brabo, Natália Casagrande [UNIFESP]; Minett, Thaís Soares Cianciarullo [UNIFESP]; Ortiz, Karin Zazo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)The objective of this study was to determine the frequency of occurrence and to characterize the typology of dysfluencies in individuals with Parkinson’s disease (PD), including the variables age, gender, schooling, disease duration, score on the Hoehn and Yahr scale and cognitive status (score on Mini-Mental State Examination). A cross-sectional study of a sample comprising 60 adults matched for gender, age and schooling was conducted. Group I comprised 30 adults with idiopathic PD, and Group II comprised 30 healthy adults. For assessment of fluency of speech, subjects were asked to utter a narrative based on a sequence of drawings and a transcription of 200 fluent syllables was performed to identify speech dysfluencies. PD patients exhibited a higher overall number of dysfluencies in speech with a large number of atypical dysfluencies. Additionally, results showed an influence of the variables cognitive status, disease duration and age on occurrence of dysfluencies.