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- ItemSomente MetadadadosAvaliação Das Alterações Cutâneas E Na Superfície Ocular Induzidas Pela Aplicação Do Laser De Co2 Fracionado Periorbital(Universidade Federal de São Paulo (UNIFESP), 2018-12-20) Sartori, Juliana De Filippi [UNIFESP]; Allemann, Norma [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Purpose: To Evaluate The Efficacy And Safety Of Periorbital Fractional Co2 Laser Resurfacing Combined Or Not To Superior Blepharoplasty. Methods: Prospective Evaluation Of 16 Female Subjects, Age Range 45 To 65 Years Old, Presenting With Photodamaged Facial Skin And Dermatochalasis. All Subjects Underwent Unilateral Periorbital Fractional Co2 Laser Resurfacing (Smartxide Co2 Laser, Deka) Treatment 30 Days Prior To Upper Blepharoplasty. Laterality Was Randomically Assigned. Quantification Of Collagen Types I And Iii Of The Treated And Untreated Palpebral Specimens Removed At Blepharoplasty Was Performed Using Histochemical Analysis And Picrosirius Red Staining. The Degree Of Periorbital Rhytidosis Was Classified Using The Kotlus Scoring System, By Two Surgeons Who Analyzed Pre And Post-Procedure Photographic Assessments. Pre- And Post-Co2 Laser Application And Blepharoplasty, Ocular Surface Was Evaluated Using Objective Parameters (Schirmer Test, Fluorescein Break Up Time - Fbut, Conjunctival Impression Citolo