Navegando por Palavras-chave "Oral mucosa cells"

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    Cytogenetic Biomonitoring in Buccal Mucosa Cells from Women Submitted to Chemotherapy After Mastectomy for Breast Cancer
    (Int Inst Anticancer Research, 2016) Souza, Ana Carolina Flygare [UNIFESP]; Silva, Victor Hugo Pereira da [UNIFESP]; Seixas, Camila [UNIFESP]; Scudeller, Tânia Terezinha [UNIFESP]; Amaral, Maria Teresa Pace do [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]
    In addition to surgery, one of the most widely applied treatments for breast cancer is chemotherapy. Chemotherapy is currently considered efficient in curing this disease
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    Cytogenetic Biomonitoring in Buccal Mucosal Cells from Municipal Solid Waste Collectors
    (Int Inst Anticancer Research, 2017) Andrade, Mariana Carvalho; Santos, Jean Nunes dos; Cury, Patricia Ramos; Souza, Ana Carolina Flygare [UNIFESP]; Claudio, Samuel Rangel [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]
    Waste collectors collect, transport, and process the garbage produced by people living in the city. Nowadays, this activity requires special attention due to the environmental impact of garbage and its potential consequences on human health. The aim of this study was to evaluate potential cytotoxic and mutagenic effects of garbage collection on waste collectors. For this purpose, a total of 47 male waste collectors aged from 24 to 53 years were included in the experimental group. A total of 30 men matched by age were used as the control group. Cytotoxicity and mutagenicity were analyzed by micronucleus test in buccal mucosaI cells. No statistically significant difference (p>0.05) in the frequency of micronuclei was detected in the waste collectors when compared to controls. Nevertheless, higher frequencies of karyolysis and pyknosis (p<0.05) were detected in buccal mucosaI cells from waste collectors when compared to matched controls. Taken together, our results indicate that waste collectors comprise an at-risk group as a result of increased cytotoxicity apparent from buccal mucosa cells.