Navegando por Palavras-chave "Ocular Surface"

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    Aspectos Clínicos, Inflamatórios E Qualidade De Vida Da Doença Do Enxerto Versus Hospedeiro Ocular
    (Universidade Federal de São Paulo (UNIFESP), 2018-09-27) Abud, Tulio Batista [UNIFESP]; Sousa, Luciene Barbosa De [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    This Thesis Focuses In A Broad Evaluation Of Ocular Graft Versus Host Disease (Gvhd), Describing Clinical Aspects, Inflammatory Mechanisms, A New Therapy Option And Quality Of Life. Three Clinical Studies Were Performed (4.1), (4.2) And (4.3). Clinical Study (4.1). Objective: To Investigate The Levels Of Neutrophil Enzymes In Tears Washes Of Patients With Ocular Gvhd And Patients With No Disease. Methods: Tear Washes Were Analyzed Using Elisa And Correlations Between The Groups Were Performed For Each Enzyme Analyzed. Results: Concentrations Of Four Enzymes With Neutrophilic Source [Neutrophil Elastase (En), Myeloperoxidase (Mpo) And Metalloproteinases (Mmp"S) 8 And 9] Were Statistically Greater In Patients With Ocular Gvhd As Compared With Controls. In Addition, There Was Strong Correlation Between Them. Conclusion: Neutrophil Activity Is Present In Tears Washes Of Ocular Gvhd, Especially Because Of The Enzyme Neutrophil Elastase. Clinical Study (4.2). Objectives: To Assess The Vision-Related Quality Of Life
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    Avaliação Das Alterações Cutâneas E Na Superfície Ocular Induzidas Pela Aplicação Do Laser De Co2 Fracionado Periorbital
    (Universidade Federal de São Paulo (UNIFESP), 2018-12-20) Sartori, Juliana De Filippi [UNIFESP]; Allemann, Norma [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Purpose: To Evaluate The Efficacy And Safety Of Periorbital Fractional Co2 Laser Resurfacing Combined Or Not To Superior Blepharoplasty. Methods: Prospective Evaluation Of 16 Female Subjects, Age Range 45 To 65 Years Old, Presenting With Photodamaged Facial Skin And Dermatochalasis. All Subjects Underwent Unilateral Periorbital Fractional Co2 Laser Resurfacing (Smartxide Co2 Laser, Deka) Treatment 30 Days Prior To Upper Blepharoplasty. Laterality Was Randomically Assigned. Quantification Of Collagen Types I And Iii Of The Treated And Untreated Palpebral Specimens Removed At Blepharoplasty Was Performed Using Histochemical Analysis And Picrosirius Red Staining. The Degree Of Periorbital Rhytidosis Was Classified Using The Kotlus Scoring System, By Two Surgeons Who Analyzed Pre And Post-Procedure Photographic Assessments. Pre- And Post-Co2 Laser Application And Blepharoplasty, Ocular Surface Was Evaluated Using Objective Parameters (Schirmer Test, Fluorescein Break Up Time - Fbut, Conjunctival Impression Citolo