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- ItemSomente MetadadadosGestational sac volume by 3D-sonography at 7-10 weeks of pregnancy using the VOCAL method(Springer, 2009-06-01) Rolo, Liliam Cristine [UNIFESP]; Machado Nardozza, Luciano Marcondes [UNIFESP]; Araujo Junior, Edward [UNIFESP]; Nowak, Paulo Martin [UNIFESP]; Moron, Antonio Fernandes [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Establish normative data for gestational sac volume (GSV) between 7 and 10 weeks gestation using three-dimensional ultrasonography (3DUS).A cross-sectional study involving 74 normal pregnancies was performed to assess GSV between 7 and 10 weeks gestation. All measurements were performed using an endocavitary volumetric transducer. the virtual organ computer-aided analysis (VOCAL) method was used for volumetric calculations, with a 30A degrees rotation angle. To analyze the correlation between GSV and gestational age, regression models were constructed and adjustments were made using the determination coefficient (R (2)). for each week the mean, median, standard-deviation, minimum and maximum GSV values were calculated. the method proposed by Royston and Wright was used to calculate the reference intervals according to crown-rump length (CRL). the interclass correlation coefficient (ICC) and Bland-Altman graph were used to evaluate intraobserver variability.There was a high correlation between GSV and gestational age (R (2) = 0.816). Mean GSV increased from 8.50 cm(3) at 7 weeks to 44.35 cm(3) at 10 weeks. There was also a significant correlation between GSV and CRL (R (2) = 0.693) with mean GSV increasing from 5.00 to 50.28 cm(3) for CRL between 9 and 40 mm. Intraobserver variability was excellent with an ICC = 0.9997 (95% CI, 0.9994-0.9998), with an average difference between measurements of 0.5 cm(3).There is a correlation between GSV and CRL and this is a reproducible first trimester parameter. Reference limits for GSV using 3DUS were generated for pregnancies between 7 and 10 weeks.
- ItemSomente MetadadadosNomogram of amniotic fluid volume at 7 to 10+6 weeks of pregnancy by three-dimensional ultrasonography using the rotational method (VOCAL)(Springer, 2010-02-01) Rolo, Liliam Cristine [UNIFESP]; Machado Nardozza, Luciano Marcondes [UNIFESP]; Araujo Junior, Edward [UNIFESP]; Nowak, Paulo Martin [UNIFESP]; Moron, Antonio Fernandes [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)To establish normative data for amniotic fluid volume (AFV) between 7 and 10 + 6 weeks gestation using three-dimensional ultrasonography (3DUS).A cross-sectional study involving 74 normal pregnancies was performed to assess AFV. All measurements were performed using an endocavitary volumetric transducer. the VOCAL (virtual organ computer-aided analysis) method was used for volumetric calculations, with a 30A degrees rotation angle. the AFV was obtained subtracting the embryonic volume from the amniotic sac volume. To analyze the correlation between AFV and gestational age, regression models were constructed and adjustments were made using the determination coefficient (R (2)). the following AFV values were obtained for each week: mean, median, standard deviation, minimum and maximum. the method proposed by Royston and Wright was used to calculate the reference intervals according to crown-rump length (CRL).Mean AFV increased from 3.97 cm(3) (range 1.17-10.97 cm(3)) at 7 to 7 + 6 weeks to 23.33 cm(3) (ranging from 11.93 to 32.41 cm(3)) at 10 to 10 + 6 weeks of pregnancy. There was a significant correlation between AFV and gestational age (R (2) = 0.635) and between AFV and CRL (R (2) = 0.756). Mean AFV increased from 7.81 cm(3) (ranging from 0.18 to 15.43 cm(3)) to 50.28 cm(3) (range 16.49-84.07 cm(3)) for CRL between 12 and 40 mm.Reference limits for AFV using 3DUS were generated for pregnancies between 7 and 10 + 6 weeks according to CRL.