Navegando por Palavras-chave "Neoplasia pulmonar"

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    Calcitonina monomérica plasmática e hipercalcemia em pacientes portadores de neoplasia pulmonar
    (Associação Médica Brasileira, 1997-06-01) Coifman, R. [UNIFESP]; Weforte, R.v.b. [UNIFESP]; Kasamatsu, T.s. [UNIFESP]; Fukusima, L. [UNIFESP]; Santoro, I. [UNIFESP]; Jamnik, S. [UNIFESP]; Vieira, J.g.h. [UNIFESP]; Lazaretti-Castro, Marise [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    BACKGROUND. Calcitonin (CT) is a peptidic hormone produced by the thyroid C cells and related to calcium metabolism. High plasmatic levels of this hormone are found in patients with medullary thyroid carcinoma, what makes it an excellent tumor marker for this disease. However, there are reports that showed an increase of plasmatic CT levels in patients with other tumors, mainly in lung cancer. PURPOSE. These data prompt us to investigate the validity of the CT level determinations as a potential tumor marker in different histologic lung cancer, and its correlation with hypercalcemia, a very common complication in these tumors. METHOD. Blood were sampled from 56 patients with malignant lung disease for the CT and ionized calcium determinations. Calcitonin was measured using a specific radioimmunoassay for the monomeric form of the molecule, in a previous silica extracted serum probe. RESULTS. We did not find elevated levels of monomeric CT in lung cancer. Only 3 patients had mild elevated levels, while in the others CT was normal or undetectable. Hypercalcemia was found in 21.4% of these patients, but only one with supranormal CT levels. CONCLUSION. Monomeric CT serum levels are normal in lung cancer, what makes the latter use an unreliable tumor marker.
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    Intervenção fisioterapêutica pré-operatória para pacientes submetidos à ressecção pulmonar por câncer: revisão sistemática
    (Pontifícia Universidade Católica do Paraná, 2013-09-01) Rosa, Bruno Rodrigues [UNIFESP]; Vital, Flávia Maria Ribeiro; Silva, Brenda Nazaré Gomes da [UNIFESP]; Lisboa, Sandra; Peccin, Maria Stella [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Iguaçu; Instituto Fernandes Figueira/Fundação Oswaldo Cruz
    INTRODUCTION: The physiotherapy has been advocated as an important component in the treatment and prevention of postoperative pulmonary complications, being used in both pre and postoperative periods of lung resection surgery. The objective of this study was to assess the efficacy and safety of preoperative physiotherapy for patients who will undergo resection surgery for lung cancer. MATERIALS AND METHODS: Systematic review of randomized clinical trials carried out in accordance with the Cochrane metodology. The electronic search was performed in Cochrane Library, PEDro, MEDLINE, EMBASE, CINAHL, LILACS. We also searched for both non-published and on-going studies in the Current Controlled Trials database. In addition, a manual search in the references of all relevant studies was performed, and the authors were contacted for additional non-published data. RESULTS: Twenty-eight papers were considered potentially relevant; among them, 26 were excluded. Two randomized controlled trials met the inclusion criteria. One study compared non invasive ventilation (BILEVEL) associated to standard treatment with standard treatment alone; and other study compared inspiratory muscle training and incentive spirometry with no training. There was just one common outcome between the studies, but was not possible to perform the meta-analysis due to missing data. CONCLUSION: There is no sufficient evidence to state that the preoperative physiotherapeutic intervention has efficacy and safety for patients who will undergo resection surgery for lung cancer.