Navegando por Palavras-chave "Modulação Simpatovagal"

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    Avaliação do controle autonômico baseada na análise da variabilidade da frequência cardíaca: proposta de método otimizado para ativação vagal e aplicação da ferramenta para estimativa da dor em intervenções clínicas
    (Universidade Federal de São Paulo (UNIFESP), 2019-03-15) Scassola, Catharina Maria Carvalho [UNIFESP]; Casali, Karina Rabello [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    The cardiac homeostasis hinge on the dynamic balance between the sympathetic and parasympathetic branches of the autonomic nervous system (ANS). Most daily activities reflect a balance between these autonomic subdivisions, with sympathetic activity being dominant in stress situations, whilst vagal is associated with rest and digestion functions. Control of cardiac homeostasis occurs especially through sympathetic and parasympathetic nerve endings scattered throughout the heart, which directly interfere with heart rate and beat-to-beat variability. As the action of such branches occurs differently, heart rate variability (HRV) analysis provides information about the regulation of heart rhythm dictated by the central nervous system through sympathetic and parasympathetic nerve discharge. Studies defend that HRV will become an indispensable clinical measure in the following years thanks to its noninvasiveness and sensibility to the detection of several clinical complications, having valuable diagnostic and prognostic attributes. One of the proposed applications of the HRV analysis in a clinical setting is in the quantification of pain through the sympathetic activation usually present. Maneuvers of sympathetic and vagal activation are used in order to evaluate the ANS through HRV analysis, quantifying the individual autonomic response in physiological and pathological situations. The maneuver used for vagal activation has limitations that can induce effects contrary to those desired. This work is divided on two fronts. In the first part, we propose a method to optimize the intervention through more homogeneous autonomic responses. Such methodology can be used for both relaxation and clinical purposes. The HRV spectral analysis was used to support the proposal of this new method for the evaluation of autonomic control during the controlled ventilation maneuver in volunteers. In the second part, we evaluated the autonomic profile (through HRV) and the pain level of pre and postsurgical patients in order to observe the clinical effects of two different surgical approaches.