Navegando por Palavras-chave "Milk allergy"

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    Conhecimento e prática de pediatras e nutricionistas sobre o tratamento da alergia às proteínas do leite de vaca no lactente
    (Universidade Federal de São Paulo (UNIFESP), 2017-03-31) Faria, Dayane Pedra Batista de [UNIFESP]; Morais, Mauro Batista de [UNIFESP]; Speridião, Patrícia da Graça Leite; Cortez, Ana Paula Bidutte; http://lattes.cnpq.br/7520873457028761; http://lattes.cnpq.br/9278345593239515; http://lattes.cnpq.br/5056114729141952; http://lattes.cnpq.br/1570443616379121; http://lattes.cnpq.br/1570443616379121; Universidade Federal de São Paulo (UNIFESP)
    Objective: Evaluate the knowledge and practice of pediatricians and nutritionists regarding cow's milk allergy (APLV) in infants, with emphasis on issues related to exclusion diet and nutritional status. Methods: Cross-sectional, descriptive study that enrolled convenience sample of 204 pediatricians and 202 nutritionists. Participants were randomly invited to 5 scientific events held in the city of São Paulo, from 2014 to 2016. Data was collected through structured and self-administered form. Results: Daily calcium recommendation for children up to 36 months of age was correctly indicated by 27.0% of pediatricians and 46.0% of nutritionists (p=0.001). Products not suitable as cow's milk substitutes were recommended by 1.5% and 21.0% of respondents. However, the reading of labels of industrialized products, 96.1% of pediatricians and 82.7% of nutritionists (p <0.001) instructed parents to read the terms that indicate the presence of milk in the food. Regarding the expressions/ingredients that should be excluded from the APLV patient's diet, it was observed that the professionals reported respectively: lactoalbumin 74.0% and 46.5% (p<0.001), casein 81.4% and 62, (P<0.001), caseinate 62.3% and 50.0% (p=0.169), milk compound 79.9% and 49.0% (p <0.001), serum proteins 71.1% and 62 , 9% (p = 0.098) and milk yeast 58.8% and 35.1% (p <0.001). Conclusions: results suggest that pediatricians and nutritionists present gaps in knowledge about the treatment of APLV in infants. Educational strategies that increase the knowledge of these professionals are important for the adequate management of APLV.
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    Contribution of Molecular Allergen Analysis in Diagnosis of Milk Allergy
    (Current Medicine Group, 2017) Bartuzi, Zbigniew; Cocco, Renata Rodrigues [UNIFESP]; Muraro, Antonella; Nowak-Wegrzyn, Anna
    Purpose of Review We sought to describe the available evidence supporting the utilization of the molecular allergen analysis (MAA) for diagnosis and management of cow milk protein allergy (CMPA). Recent Findings Cow milk proteins are among the most common food allergens in IgE- and non-IgE-mediated food allergic disorders in children. Most individuals with CMPA are sensitized to both caseins and whey proteins. Caseins are more resistant to high temperatures compared to whey proteins. Summary MAA is not superior to the conventional diagnostic tests based on the whole allergen extracts for diagnosis of CMPA. However, MAA can be useful in diagnosing tolerance to extensively heated milk proteins in baked foods. Children with CMPA and high levels of casein IgE are less likely to tolerate baked milk compared to children with low levels of casein IgE. Specific IgE-binding patterns to casein and betalactoglobulin peptides may predict the natural course of CMPA and differentiate subjects who are more likely to develop CMPA at a younger age versus those with a more persistent CMPA. Specific IgE-binding patterns to casein and beta-lactoglobulin peptides may also predict response to milk OIT and identify patients most likely to benefit from OIT.
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    Acesso aberto (Open Access)
    Teste de desencadeamento aberto no diagnóstico de alergia à proteína do leite de vaca
    (Sociedade Brasileira de Pediatria, 2010-04-01) Correa, Fernanda Ferreira [UNIFESP]; Vieira, Mário César; Yamamoto, Danielle Reis; Speridião, Patrícia da Graça Leite [UNIFESP]; Morais, Mauro Batista de [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Hospital Pequeno Príncipe Centro de Gastroenterologia Pediátrica
    OBJECTIVES: To report the results of open challenge tests performed in children fed with cow's milk-free diet. DESCRIPTIONS: Cross-sectional study evaluating cow's milk open challenge performed under supervision in a hospital setting during 2.5 hours and ambulatory follow-up for 30 days when no immediate reaction occurred. One hundred and twenty-one patients were included, with ages between 4 and 95 months. Cow's milk open challenge tests were positive in 28 patients (23.1%). A clinical manifestation of cow's milk allergy different from the one presented at diagnosis occurred in 12 (24.9%) patients with positive challenge. Positive challenge was more frequent (p = 0.042) in patients fed with extensively hydrolyzed formulae or amino acid-based formulae (30.3%) when compared to those fed with other exclusion diets (14.5%). CONCLUSION: Open challenge allowed the interruption of exclusion diet in a significant proportion of the patients.