Navegando por Palavras-chave "Massa Muscular"

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    Efeitos crônicos da suplementação de Citrulina Malato sobre a força e massa muscular de jovens adultos saudáveis treinados: um ensaio clínico randomizado, cruzado, duplo-cego e controlado por placebo
    (Universidade Federal de São Paulo (UNIFESP), 2020-05-05) Estanislau, Thiago Barros [UNIFESP]; Gonçalves, Daniela Caetano [UNIFESP]; Universidade Federal de São Paulo
    L-citrulline (CIT) is a non-essential amino acid, found in watermelon juice that has the ability to increase endogenous concentrations of arginine (ARG) and markers of nitric oxide (NO) production. The combination and acute use with malate (intermediate of the tricarboxylic acid cycle) has shown promising results in the field of sports nutrition, however the chronic effects are still unknown. This master thesis explored the effects of citrulline malate (CM) supplementation on strength and muscle mass measurements of healthy young adults trained at recreational level. Twenty-four men (age 25.96 ± 4.70 years, body mass 82.25 ± 10.7kg; height 1.79 ± 0.07m and BMI 25.07 ± 2.14m kg/m²) with previous experience in strength training were recruited for this randomized, double-blind, crossover, placebo-controlled study. Each participant consumed 6g of CM or placebo (PLA) at random, 60 minutes before training, for 28 days each, with 1 week of wash-out. The maximum dynamic strength (MDS) was assessed by the one maximum repetition test (1-RM) in the bench press. Body composition was determined by plethysmography. For the statistical analysis, the two-way ANOVA analysis model was used. Significance level equal to or less than 0.05 was considered. Data are represented as mean and standard deviation, or mean and 95% confidence interval (95% CI). The supplementation of CM promoted an increase in fat-free mass (FFM) (pre 67.28 kg ± 8.11 kg vs post 67.77 kg ± 7.97 kg) in relation to PLA (pre 67.83 kg ± 7.84 kg vs post 67, 43kg ± 8.57kg) (CM vs PLA,p = 0.037; CI = 95%: 0.03 - 1.21). Still, in the use of CM there was a reduction in fat mass (FM) (pre 15.10 ± 5.55 vs post 13.85 ± 4.61) in relation to PLA (pre 14.32 ± 5.34 vs post 14.65 ± 5.34) (CM vs PLA, p = 0.30; CI = 95%: -1.24 - -0.06). For FDM, there was an increase in the final load when using both supplements (CM and PLA) (T1: 36.4 (95% CI = 33.0 - 39.8) vs T2: 39.8 (95% CI = 36.4 - 43.2) vs T3 41.8 (95% CI = 38.4 - 45.2) (p = <0.001 in relation to T1 and p = <0.05 in relation to T2.) However, in the use of CM, a greater tendency to increase load was observed in in relation to PLA (p = 0.059). The results show that supplementation of CM for 4 weeks seems to be able to increase FDM and improves body composition, by increase FFM and to reduce FM.
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    Suplementação de Whey Protein em idosos com Diabetes do tipo 2 submetidos a um programa de exercícios resistidos: pesquisa clínica controlada, randomizada e duplo cego pesquisa clínica controlada e randomizada
    (Universidade Federal de São Paulo (UNIFESP), 2019-12-10) Furtado, Celine de Carvalho [UNIFESP]; Lombardi Júnior, Imperio [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    INTRODUCTION: The aging, natural and progressive process that promotes changes in body composition, physical and functional capacity, increasing the incidence of chronic diseases such as diabetes mellitus type 2 (DM2). The adoption of a healthy diet is one of the main pillars of treatment and management of DM2. Physical exercise is related to the improvement of body composition and glycemic control. Evidence suggests that whey protein supplementation presents good results in terms of stimulating muscle protein synthesis in the elderly, besides improving insulin sensitivity and glycemic control in people with DM2. AIM: Analyze the effect of whey protein supplementation on lean mass and glycemic control in elderly individuals with non-insulin dependent type 2 diabetes who underwent resistance exercise training. METHODOLOGY: This is a randomized, controlled, double-blind clinical trial of 39 60- to 80-year-old male and female patients with DM2. The participants performed the following evaluations: anamnesis, evaluation of food consumption, evaluation of physical activity level, blood collection for analysis of glycemic profile and markers of renal function, evaluation of body composition, cardiopulmonary, quality of life and strength test. Being able to participate, a progressive resistance training protocol was started twice a week, followed by supplementation with whey protein or placebo for 12 weeks. Statistical analysis was performed by SPSS version 21 and for statistical significance was considered p<0.05. RESULTS: Supplementation 27g of protein, consumed after strength training, did not bring changes in renal and glycemic markers. The supplemented group presented significant improvements in the evaluation of grip strength and quality of life (p<0.05) compared to the control group. There was no significant presence of low mass and/or low muscle strength, besides the participants good control of DM2 (glycated hemoglobin <7%). The protein intake was below the recommendation for the elderly (1.2 - 1.5g/kg/day). CONCLUSION: Was concluded that resistance training with whey protein supplementation improved the grip strength and mental aspect of the quality of life of elderly people with DM2, but did not bring increased muscle mass and reduced glycemic markers.