Navegando por Palavras-chave "Low-intensity LED"

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    Effects of low-intensity non-coherent light therapy on the inflammatory process in the calcaneal tendon of ovariectomized rats
    (Springer London Ltd, 2016) Helrigle, Carla; Camilo de Carvalho, Paulo deTarso; Casalechi, Heliodora Leao; Pinto Leal-Junior, Ernesto Cesar; Cardoso Fernandes, Guilherme Henrique; Helrigel, Panmera Almeida; Rabelo, Rogerio Leao; Aleixo-Junior, Ivo de Oliveira; Aimbire, Flavio [UNIFESP]; Albertini, Regiane
    The aim of this experimental study was to investigate the effects of low-intensity light-emitting diode (LED) phototherapy on the inflammatory process in the calcaneal tendon of ovariectomized rats (OVX) through the involvement of the inflammatory mediators interleukin (IL)-6, IL-10, and tumor necrosis factor-alpha (TNF-alpha). Thirty-five female Wistar rats were divided into 4 groups: 3 groups of OVX rats totaling 30 rats (untreated OVX rats [OVX injury group], treated OVX rats [OVX LED group], and control OVX rats subgroups existed based on the sampling times, which were 3, 7, and 14 days) and 1 group of non-OVX rats (not OVX n = 5). Tendon injury was induced by trauma using a 208-g mass placed at 20 cm from the right tendon of each animal with energy of 0.70 J. The animals were treated 12 h after tendonitis with LED therapy and every 48 h thereafter until euthanasia (at 3, 7, or 14 days). The tendons were dissected and stored in liquid nitrogen at -196 A degrees C, thawed only at the time of immunoenzymatic testing (ELISA). Groups treated with LED showed a decrease in the number of pro-inflammatory cells, IL-6, and TNF-alpha (p < 0.05), and an increase in IL-10 (p < 0.05) when compared to the not OVX group (p < 0.05). It was concluded that low-intensity LED treatment using the parameters and wavelength of 945 nm in the time periods studied reduced the release of IL-6 and TNF-alpha and increased the release of IL-10, thereby improving the inflammatory response in OVX rats.
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    Effects of low-intensity non-coherent light therapy on the inflammatory process in the calcaneal tendon of ovariectomized rats
    (Springer London Ltd, 2016) Helrigle, Carla; Camilo de Carvalho, Paulo deTarso; Casalechi, Heliodora Leao; Pinto Leal-Junior, Ernesto Cesar; Cardoso Fernandes, Guilherme Henrique; Helrigel, Panmera Almeida; Rabelo, Rogerio Leao; Aleixo-Junior, Ivo de Oliveira; Aimbire, Flavio [UNIFESP]; Albertini, Regiane
    The aim of this experimental study was to investigate the effects of low-intensity light-emitting diode (LED) phototherapy on the inflammatory process in the calcaneal tendon of ovariectomized rats (OVX) through the involvement of the inflammatory mediators interleukin (IL)-6, IL-10, and tumor necrosis factor-alpha (TNF-alpha). Thirty-five female Wistar rats were divided into 4 groups: 3 groups of OVX rats totaling 30 rats (untreated OVX rats [OVX injury group], treated OVX rats [OVX LED group], and control OVX rats