Navegando por Palavras-chave "Intracranial Pressure"

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    Characterization of intracranial pressure behavior in chronic epileptic animals: a preliminary study
    (Univ Estadual Oeste Parana-Unioeste, 2016) Cardim, Danilo Augusto; Frigieri, Gustavo Henrique; Troca Cabella, Brenno Caetano; Malheiros, Jackeline Moraes [UNIFESP]; Cardim, Ana Carolina; Wang, Charles Chenwei; Pacheco Andrade, Rodrigo de Albuquerque; Covolan, Luciene [UNIFESP]; Tannus, Alberto; Mascarenhas, Sergio
    Intracranial pressure (ICP) is a major neurological parameter in animals and humans. ICP is a function of the relationship between the contents of the cranium (brain parenchyma, cerebrospinal fluid, and blood) and the volume of the skull. Increased ICP can cause serious physiological effects or even death in patients who do not quickly receive proper care, which includes ICP monitoring. Epilepsies are a set of central nervous system disorders resulting from abnormal and excessive neuronal discharges, usually associated with hypersynchronism and/or hyperexcitability. Temporal lobe epilepsy (TLE) is one of the most common forms of epilepsy and is also refractory to medication. ICP characteristics of subjects with epilepsy have not been elucidated because there are few studies associating these two important neurological factors. In this work, an invasive (ICPi) and the new minimally invasive (ICPmi) methods were used to evaluate ICP features in rats with chronic epilepsy, induced by the experimental model of pilocarpine, capable of generating the main features of human TLE in these animals.
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    A new index for the assessment of transverse sinus stenosis for diagnosing idiopathic intracranial hypertension
    (Bmj Publishing Group, 2017) da Silveira Carvalho, Gustavo Balthazar [UNIFESP]; de Andrade Matas, Sandro Luiz [UNIFESP]; Idagawa, Marcos Hideki [UNIFESP]; Tobaru Tibana, Luiz Antonio [UNIFESP]; de Carvalho, Renato Sartori [UNIFESP]; Souza Silva, Matheus Luis [UNIFESP]; Cogo-Moreira, Hugo [UNIFESP]; Jackowski, Andrea Parolin [UNIFESP]; Abdala, Nitamar [UNIFESP]
    Background and purpose To assess the role of MR venography (MRV) for detecting transverse sinus stenosis, to determine the importance of this finding in idiopathic intracranial hypertension (IIH), and to propose an index that contributes to this diagnosis. Materials and methods We retrospectively assessed consecutive intracranial MRV of patients aged >18years diagnosed with IIH according to the diagnostic criteria, between January 2010 and July 2012. The assessments were randomly analyzed by three radiologists. Stenoses in the right and left transverse sinuses were independently classified according to the following scale: 0, normal