Navegando por Palavras-chave "Infant development"
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- ItemAcesso aberto (Open Access)Desenvolvimento motor e cognitivo de lactentes expostos ao HIV(Universidade Federal de São Paulo, 2015-02-06) Silva, Kaitiana Martins da [UNIFESP]; Carvalho, Raquel de Paula [UNIFESP]; http://lattes.cnpq.br/7980384093582831; http://lattes.cnpq.br/5254507928794942; Universidade Federal de São Paulo (UNIFESP)The main form of transmission of the Immunodeficiency virus (HIV) in children is the vertical transmission. The HIV virus has preference for cells of the immune system and from the central nervous system. It can go through the hematoencephalic barrier causing delays in the psychomotor and sociocognitive development in these children. The investigation of the motor and cognitive development of infants exposed to the H IV virus, associated with the use of an antiretroviral, is of great importance as the positive diagnostic of the HIV virus only happens around the 18th month after the child's birthday. The goal of this study was to compare the motor and cognitive development of infants exposed ant not exposed to the HIV virus on their first 18 months of age. The re were 80 infants analysed in this transversal study between ages of 4, 8, 12 and 18 months which were divided in 2 groups: Experimental Group-EG (composed by infants, children of HIV positive mothers who follow medical treatment at the center of reference in the city of Santos) and Control Group-CG (composed of infants of mothers who were not exposed to the HIV virus). As evaluation tools the Bayley Scale of Infant and Toddler Development III (BSITD III) were used. The results demonstrated differences for the factor group in the motor and cognitive domain, and there were higher scores for the CG compared to the EG, regardless of the age. It was verified by the EG infants lower scores for the cognitive domain in the 8th and 18th month. In the categories of classification of the motor and cognitive development, the babies were classified as average, except one baby from the EG group with 18th months for motor development. To conclude, the infants who were exposed to the HIV and the antiretroviral therapy dont show alterations in the motor and cognitive development in the first 18 months of life but they show lower cognitive development in the 8th and 18th month.
- ItemSomente MetadadadosGrowth of children born to renal transplanted women(Springer, 2017) Dinelli, M. Isabel S. [UNIFESP]; Ono, Erika [UNIFESP]; Viana, Patricia O. [UNIFESP]; dos Santos, Amelia M. N. [UNIFESP]; Isabel de Moraes-Pinto, M. [UNIFESP]Neonates born to transplanted mothers are exposed to immunosuppressive drugs during gestation and have a higher risk of being born prematurely and small for gestational age than the general population. We have prospectively followed up 27 children born to renal transplanted mothers from a single center and 31 healthy children born at term with adequate weight for gestational age. Comparisons of weight and length measurements were made at birth, 1 month (+/- 0.9), 3 months (+/- 1.0), 6 months (+/- 1.0), 9 months (+/- 1.5), and 12 months (+/- 1.49) of age. There were a high rate of prematurity (51.9%) and neonates small for gestational age (40.7%) in the transplant group. At birth, in the transplant group, 28% of neonates had subnormal z-scores for weight and 40%, low z-scores for length. However, at 6 months of age, no significant differences were noticed in mean weight-for-age z-scores between groups (weight -0.43 vs -0.03
- ItemAcesso aberto (Open Access)Risk factors associated with developmental abnormalities among high-risk children attended at a multidisciplinary clinic(Associação Paulista de Medicina - APM, 2008-01-01) Resegue, Rosa [UNIFESP]; Puccini, Rosana Fiorini [UNIFESP]; Silva, Edina Mariko Koga da [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)CONTEXT AND OBJECTIVE: Knowledge of risk factors associated with child development disorders is essential for delivering high-quality childcare. The objective here was to evaluate the relationships between risk factors and occurrences of developmental abnormalities among children attended at a reference clinic for children at risk of developmental abnormalities. DESIGN AND SETTING: Retrospective study at a multidisciplinary reference center, Embu, São Paulo. METHODS: All cases followed up for more than three months between 1995 and 2003 were reviewed. The risk factors assessed were low birth weight, gestational age, length of stay in neonatal ward, perinatal asphyxia, mother s age < 18 years, congenital infections, malformations and low mother s education level. Developmental abnormalities were defined according to developmental tests and assessments by the clinic s professionals. The statistical analysis consisted of the chi-squared test for comparing categorical variables and a logistic regression model for multivariate analysis. RESULTS: 211 children were followed up for more than three months. Developmental abnormalities occurred in 111 (52.6%). Univariate analysis showed significant relationships between developmental abnormality and low birth weight, perinatal asphyxia, length of stay > 5 days, prematurity and mother s age 18 years and older. Low birth weight, history of perinatal asphyxia and mother s age continued to be significant in multivariate analysis. CONCLUSIONS: Special attention must be paid to the development of low birth weight infants and/or infants with histories of neonatal complications. Low birth weight is easily assessed and should be considered to be an important marker when defining guidelines for following up child development.