Navegando por Palavras-chave "Imidazolium salts"
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- ItemAcesso aberto (Open Access)Aplicação de líquidos iônicos na extração de carotenoides provenientes do tomate para uso em alimentos como ingrediente bioativo(Universidade Federal de São Paulo (UNIFESP), 2016-10-08) Martins, Paula Larangeira Garcia [UNIFESP]; De Rosso, Veridiana Vera [UNIFESP]; http://lattes.cnpq.br/4938721558237749; http://lattes.cnpq.br/2339710145228308; Universidade Federal de São Paulo (UNIFESP)Ionic liquid (IL) aplication in extractions process is a viable alternative that follow the Green Chemistry principle, minimazing contamination and optmaizing the obtain of importante natural pigments such as carotenoids. The lycopene in prevention of various diseases has been the subject of numerous studies that demonstrate beneficial effect on human health. This study evaluated the application of commercial and synthesized ionic liquids to obtain carotenoids from tomato for use as bioactive ingredient, and determined the stability, antioxidant activity and toxicity of optimized extract. Tomatoes from disposal were obtained from the Municipal Market Santos without any ranking or previous fruits selection. Four different ionic liquids were tested as extractors, tetrafluoroborate of 1-n-butyl-3-methylimidazolium chloride and 1-n-hexyl-3-methylimidazolium from commercial sources; chloride 1-n-butyl-3-methylimidazolium hexafluorophosphate and 1-n-butyl-3-methylimidazolium synthesized. The determination of qualitative and quantitative carotenoid obtained was performed by HPLC-PAD-MS / MS. The toxicological tests have been developed in animal models, administering the extracts by gavage for seven days and the collected fabrics were evaluated for histological features of the liver and kidneys; additionally checking the genotoxic and mutagenic potential. The synthesis of ionic liquids was adapted and assisted by ultrasound, resulting in a fully product obtained without the use of volatile organic solvents. In the process for obtaining carotenoids, in particular lycopene, was extracted into all-trans lycopene concentrations ranging 7.5 to 8.0 ?g.g-1 tomato extracted with acetone and IL respectively. The thermal stability of the carotenoid extract obtained by IL resulted in activation energy (Ea) in an aqueous medium similar to conventional values in acetone. The antioxidant activity of tomatoes carotenoid extract in ionic liquid was 7.4 ?-tocopherol equivalent and acetone 12.4. The carotenoid extract obtained by IL administered at 10 mg/kg/day dose led the formation of a smaller number of micronuclei (4.2 ± 2.2 in 2000 bone marrow cells of exposed animals) compared to the control group (5.7 ± 3.3). The extract obtained by the method developed remained stable in aqueous and oily medium and obtained higher yield than the conventional method. Thus, the use of IL in the extraction of tomato carotenoids presents technical feasibility.
- ItemSomente MetadadadosCan ionic liquid solvents be applied in the food industry?(Elsevier Science London, 2017) Martins, Paula Larangeira Garcia [UNIFESP]; Braga, Anna Rafaela Cavalcante [UNIFESP]; Rosso, Veridiana Vera de [UNIFESP]Background: Currently, increased attention is drawn to replacing volatile organic solvents used for extraction with ionic liquids (ILs). ILs are organic salts consisting entirely of ions, having melting points below 100 degrees C and being a promising alternative to traditional volatile organic solvents from both environmental and technological perspectives. Scope and approach: Despite being extensively researched, ILs have not yet been evaluated as ecofriendly solvents for the food industry, which is the aim of the present work. Based on literature data on the use of ILs as extractants and their toxicities and biological activities, we conclude that their utilization as food industry solvents is a promising research area due to the possibility of solvent recycling. Key Findings and Conclusions: Despite the lack of information on the toxicity of food products contaminated by residual ILs, low doses of ILs in animal and in vitro tests resulted in no cell damage. Thus, new applications of ILs in the food industry are possible, addressing the limitations and needs of each process. (C) 2017 Elsevier Ltd. All rights reserved.
- ItemSomente MetadadadosThermal and light stabilities and antioxidant activity of carotenoids from tomatoes extracted using an ultrasound-assisted completely solvent-free method(Elsevier Science Bv, 2016) Martins, Paula Larangeira Garcia [UNIFESP]; Rosso, Veridiana Vera de [UNIFESP]The use of petroleum-derived solvents, particularly volatile organic compounds (VOCs), in the chemical industry has increased the contamination and residual effects of these solvents. Ionic liquids (ILs) can potentially replace VOCs, thereby reducing the risks of environmental contamination and toxicity. In this context, the objectives of this study were as follows: 1 - to obtain an ionic liquid for use in extracting carotenoids from tomatoes with ultrasound assistance