Navegando por Palavras-chave "Hipotálamo Ventromedial"

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    O papel da neurotransmissão mediada por CRF do hipotálamo dorsomedial e ventromedial sobre a modulação de diferentes respostas comportamentais de defesa
    (Universidade Federal de São Paulo (UNIFESP), 2018-10-18) Faria, Mariana Santos Carvalho de [UNIFESP]; Viana, Milena de Barros [UNIFESP]; http://lattes.cnpq.br/3053794724319601; Universidade Federal de São Paulo (UNIFESP)
    Corticotrophin Releasing Factor (Crf) Plays A Critical Role In Mediation Of Physiological And Behavioral Responses To Stress. Based On The Role Of The Medial Hypothalamus In Defense-Related Behavioral Responses, And In A Previous Study Demonstrating That Crf Administration In The Dorsomedial (Hdm), A Region That Modulates Defensive Reactions, Was Shown To Facilitate Elevated T-Maze (Etm) Avoidance Responses, An Anxiogenic-Like Effect. Intra-Hdm Administration Of The Crf Type 1 Receptor (Crfr1) Antagonist Antalarmin Induced Anxiolytic-Like Effects And Counteracted The Anxiogenic Effects Of Crf. The Present Study Further Investigates The Role Played By Crf Receptors Of The Medial Hypothalamus In Anxiety. For That, Male Wistar Rats Were Treated With Crfr1 And Crfr2- Modulating Drugs In The Hdm Or Hvm, Another Hypothalamic Nucleus Implicated With Defensive And Emotional Behavior, And Tested In The Etm For Inhibitory Avoidance And Escape Measurements. In Clinical Terms, These Responses Have Been Respectively Relat