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- ItemSomente MetadadadosAir pollution and its relationship to lung function among adolescents from Taubate, Sao Paulo, Brazil(Elsevier Doyma Sl, 2018) Toledo, M. Froio; Saraiva-Romanholo, B. Mangueira; Oliveira, R. Carvalho; Silva, L. Ferraz da; Solé, Dirceu [UNIFESP]Background: This paper sought to evaluate individual exposure to air pollution by quantifying the carbon in alveolar macrophages (AMs) and its relationship to lung function. We also examined the proximity of participants' residences to the Presidente Dutra highway (PDH) in adolescents with asthma from Taubate, Sao Paulo, Brazil. Methods: This descriptive study examined fifty 13- to 14-year-old adolescents with asthma identified by the International Study of Asthma and Allergies in Childhood (ISAAC) in Taubate. These adolescents underwent spirometry and sputum induction via the inhalation of 3% hypertonic saline (HSS). Sputum was collected after each nebulisation, and forced expiratory flow in one second (FEV1) was measured. The collected sputum was stored and transported to the laboratory
- ItemSomente MetadadadosChanges over time in the prevalence of asthma, rhinitis and atopic eczema in adolescents from Taubate, Sao Paulo, Brazil (2005-2012): Relationship with living near a heavily travelled highway(Elsevier Doyma Sl, 2016) Totedo, M. F.; Saraiva-Romanholo, B. M.; Oliveira, R. C.; Saldiva, P. H. N.; Silva, L. F. F.; Nascimento, L. F. C.; Sole, D. [UNIFESP]Background: The prevalence of allergic diseases is increasing. We evaluated temporal trends in the prevalence of asthma, rhinitis and eczema in adolescents (13-14 years) living in Taubate, SP, Brazil (2005-2012) and assessed the relationship between these prevalences and the residential proximity to Presidente Dutra Highway (PDH, a heavily travelled highway). Methods: This cross-sectional study of adolescents (N=1039) from public and private schools was evaluated using the standard questionnaire of the International Study of Asthma and Allergies in Childhood (ISAAC) plus a question about their place of residence in relation to PDH. The data obtained were compared to the 2005 data using a chi-square test or Fisher's exact test. An analysis by groups consisting of two phases (two-step cluster) was used to evaluate the effect of living near PDH. Results: There was a lifetime increase in the prevalence of active asthma (15.3% vs. 20.4%, p = 0.005) and physician-diagnosed asthma (6.8% vs. 9.2%, p = 0.06) and a decrease in the symptoms of active rhinitis (36.6% vs. 18.5%) between 2005 and 2012. A high frequency of asthma and rhinitis (18.1% vs. 23.2%, respectively) was observed among adolescents living close or very close to PDH